Doctor’s Passport

Find your next topic

Explore the current textbook

Available drafts · Clinical review pending
Membership
Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
Rapid

Perioperative fluid therapy

Essential points for quick revision.

Saved on this device
!
Shock needs simultaneous diagnosis

Hypotension, tachycardia, altered consciousness, cold peripheries, prolonged capillary refill, oliguria or rising lactate may indicate hypovolaemia, but bleeding, sepsis, cardiac failure, obstruction and anaesthetic effects require different definitive treatment.

Action: Use an ABCDE assessment, control haemorrhage and call senior help, give an indicated crystalloid bolus with immediate reassessment, and activate the applicable haemorrhage, sepsis or organ-support pathway instead of repeating fluid blindly.

Synopsis

Prescribe and reassess intravenous fluid for an adult surgical patient by separating resuscitation, routine maintenance, replacement and redistribution while preventing sodium, chloride, glucose and volume-related harm.

  • Start with the five Rs: Resuscitation, Routine maintenance, Replacement, Redistribution and Reassessment. State which indication each prescribed bag is treating.
  • For adult resuscitation under CG174, use crystalloid containing sodium 130–154 mmol/L, give 500 mL over less than 15 minutes, then reassess before any further bolus.
  • For routine maintenance alone, begin with 25–30 mL/kg/day water, about 1 mmol/kg/day each of sodium, potassium and chloride, and 50–100 g/day glucose; use less in older, frail, renal or cardiac patients.

Key red flags

Persistent instability or worsening lactate after an initial bolus demands diagnostic escalation; repeated litres can delay haemorrhage control or worsen cardiogenic and obstructive shock.

New hypoxaemia, crackles, raised jugular venous pressure or increasing peripheral oedema after fluid suggests overload and requires reassessment rather than completion of the prescription.

Oliguria alone is not proof of intravascular depletion; obstruction, acute kidney injury, sepsis and drug effects must be considered before more fluid.

Severe renal or liver disease, pregnancy, burns and diabetes lie outside CG174 general prescriptions and require matched specialist guidance.

Marked sodium, potassium, glucose or acid-base disturbance cannot be corrected safely by copying a routine maintenance bag.

Active blood loss requires bleeding control, component support and a major-haemorrhage approach when indicated; crystalloid is not a substitute for oxygen-carrying capacity and haemostasis.

Failure to respond

Ongoing hypotension, deteriorating perfusion, rising lactate or new pulmonary oedema after a bolus indicates an unsafe trajectory and requires immediate senior diagnostic review.

Reasoning priorities

01
Clinical fluid assessment and passive leg raise

Estimate perfusion, congestion and potential fluid responsiveness before and after an intervention.

Haemodynamic improvement within about 30–90 seconds supports possible volume responsiveness; breathlessness or deterioration suggests overload, but neither response identifies the cause of shock alone.

Worked reasoning

Worked case: postoperative hypotensionLow pressure after abdominal surgery

An adult in recovery is tachycardic and hypotensive with cool peripheries after an operation where blood loss may have been underestimated.

  1. Perform ABCDE assessment, call senior anaesthetic and surgical help, review theatre fluid and blood loss, inspect drains and wound, and obtain haemoglobin, lactate, acid-base and coagulation data as indicated.
  2. If hypovolaemia remains likely, give 500 mL crystalloid containing sodium 130–154 mmol/L over less than 15 minutes while arranging haemorrhage control and matched blood support if bleeding is significant.
  3. Reassess observations, perfusion, lungs, venous pressure, mental state, urine and lactate immediately; do not prescribe the next bolus before deciding whether response supports further fluid.
  4. If instability persists, escalate source control, haemorrhage management, vasopressor or cardiac assessment according to cause instead of treating every low pressure with crystalloid.
  5. Once stable, recalculate maintenance and measured replacement separately and document review timing, biochemical monitoring and limits for stopping fluid.
Routine maintenance pathwayStable adult temporarily unable to drink

The patient is haemodynamically stable, has no major deficit or abnormal loss and cannot meet needs enterally for the next day.

Key medicines

Sodium-containing crystalloid for resuscitationGive 500 mL containing sodium 130–154 mmol/L over less than 15 minutes, then reassess.Use smaller or slower challenges when cardiac or renal reserve is limited; repeated unassessed boluses risk pulmonary oedema and delayed source control.
Routine-maintenance IV fluidInitially provide 25–30 mL/kg/day water with about 1 mmol/kg/day each sodium, potassium and chloride.Reduce water for frailty or cardiac and renal impairment; supply 50–100 g/day glucose, avoid adding potassium directly to bags, and monitor.
Open full textbook Answer 2 questions
Sources and review status3 sources · checked 13 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 13 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom