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Galactocele

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Synopsis

Recognise a milk-retention cyst during or after lactation, distinguish it from abscess and solid tumour on imaging, and use aspiration or biopsy when symptoms, infection or discordance require intervention.

  • A galactocele is a milk-retention cyst caused by duct obstruction during pregnancy, breastfeeding or soon after weaning and commonly presents as a painless mobile mass.
  • Ultrasound appearances vary with fat, protein and water content; a fat-fluid level is suggestive, while thick contents can create internal echoes that resemble a solid lesion.
  • Clinical and imaging assessment must localise the same mass because lactation does not protect against fibroadenoma, abscess or pregnancy-associated breast cancer.

Investigation priorities

01
Targeted ultrasoundFirst step

Confirm cystic anatomy, assess internal contents and plan a safe route for diagnostic sampling or therapeutic drainage.

Management branches

Concordant observation pathwayManage a comfortable milk-retention cyst

A breastfeeding patient has a 2 cm mobile lump; ultrasound shows a classic fat-fluid cyst with no vascular solid component.

  1. Map the mass and assess feeding, weaning changes, pain, fever, skin and nodes so the imaging is correlated with the actual target.
  2. Explain the milk-retention mechanism and offer observation because the lesion is small, comfortable and radiologically concordant.
Infected galactocele pathwayTreat an infected milk collection

A galactocele becomes hot and tender with fever and turbid fluid. After urgent assessment, the breastfeeding adult is stable without sepsis, spreading cellulitis or threatened skin; renal function is preserved, the infant is healthy and term, and there is no beta-lactam allergy or MRSA risk.

Key medicines

Flucloxacillin for an infected lactational galactoceleAfter assessment and drainage, the NHS Highland adult breast-abscess example is flucloxacillin 500 mg orally four times daily for 7–10 days. Apply it to a stable patient without relevant allergy or MRSA risk, then review culture and improvement; this differs from the NHS Dumfries & Galloway 10–14-day mastitis pathway.Use the 500 mg capsules on an empty stomach, one hour before or two hours after meals, with 250 mL water and no immediate lying down. Exclude beta-lactam or product hypersensitivity and previous flucloxacillin-associated jaundice/liver dysfunction. Review hepatic disease and interactions including methotrexate, warfarin/INR, probenecid and voriconazole. CrCl under 10 mL/min needs prescriber consideration of a reduced dose or extended interval. Concurrent paracetamol in severe renal impairment, sepsis or malnutrition requires acidosis-risk review and monitoring. Monitor the healthy term infant for gastrointestinal symptoms, thrush, rash or feeding difficulty; severe maternal illness or an unwell/premature infant needs individual specialist advice.
Lidocaine 10 mg/mL for drainage-site anaesthesiaUse plain Aguettant 1% lidocaine by local intradermal/subcutaneous infiltration, selecting the minimum effective volume. The product gives a usual adult infiltration total of 3–5 mg/kg and a generally recommended 200 mg ceiling, equivalent to 20 mL. Do not aim for the ceiling; adjust the dose to the patient and procedure.An experienced clinician with resuscitation facilities should administer it. Amide-local-anaesthetic/product allergy excludes use; cardiac or liver insufficiency may need up to a half-dose reduction, and renal impairment or frailty can require further individual adjustment. Review conduction disease, seizures, anticoagulants, other local anaesthetics and antiarrhythmic/metabolic interactions. Infected tissue has poorer anaesthetic effect and greater systemic absorption; avoid intravascular injection and monitor for toxicity. Stop and initiate urgent assessment/resuscitation for perioral sensory change, tinnitus, seizures, arrhythmia or collapse. The IVRA 3 mg/kg maximum and adrenaline-mixture rules are not infiltration rules; recommended local doses are compatible with continued breastfeeding.
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Sources and review status8 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom