Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
2 min synopsisUK scopeSources checked 25 Aug 2026Clinical review pending
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Escalate
Clinic BP 180/120 mmHg or higher requires an immediate target-organ-damage and symptom screen. Arrange same-day specialist assessment when this is accompanied by retinal haemorrhage or papilloedema, new confusion, chest pain, signs of heart failure or acute kidney injury; also refer same day if phaeochromocytoma is suspected. Treat the clinical emergency and organ injury, not the number alone.
Synopsis
Recognise, confirm and stage adult hypertension; identify same-day emergencies; start evidence-based treatment and monitor safely in UK practice.
Measure BP with the person seated, relaxed, arm supported and an appropriately sized cuff; check the pulse first and use manual auscultation if it is irregular.
Measure both arms initially. If the difference remains greater than 15 mmHg after repeat measurement, use the arm with the higher reading thereafter.
Clinic BP 140/90 to 179/119 mmHg should usually be confirmed by ABPM; use HBPM if ABPM is unsuitable or not tolerated.
Key red flags
Severe hypertension without emergency features
BP 180/120 mmHg or higher but no retinal haemorrhage/papilloedema and no life-threatening symptoms: promptly test for target-organ damage. If none is found, confirm with ABPM/HBPM or repeat clinic BP and complete clinical review within 7 days.
Investigation priorities
01
Repeat standardised clinic BP in both armsFirst step
Confirm the initial reading and identify an inter-arm difference.
02
ABPMPreferred
Preferred confirmation for clinic BP 140/90 to below 180/120 mmHg.
Management branches
NICE diagnosisConfirm and risk-stratify
Clinic BP 140/90 to below 180/120 mmHg without emergency features.
Repeat clinic BP correctly, arrange ABPM or HBPM, and simultaneously investigate target-organ damage; do not wait for out-of-office confirmation before investigating.
Document stage, standing BP where indicated, comorbidity, medicines/substances, family history, lifestyle and QRISK3.
RamiprilUsually 2.5 mg orally once daily; start 1.25 mg once daily with marked renin-angiotensin activation or relevant diuretic use, then double at 2–4-week intervals to a maximum 10 mg/day according to response and tolerance.
Losartan50 mg orally once daily; consider 25 mg once daily if intravascularly depleted, and increase to 100 mg once daily after response review, typically from about 1 month.
National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 25 Aug 2026; clinical approval remains outstanding.