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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
RapidNICE NG136ABPMresistant hypertensionhypertensive emergencyprescribing

Hypertension

Essential points for quick revision.

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Escalate

Clinic BP 180/120 mmHg or higher requires an immediate target-organ-damage and symptom screen. Arrange same-day specialist assessment when this is accompanied by retinal haemorrhage or papilloedema, new confusion, chest pain, signs of heart failure or acute kidney injury; also refer same day if phaeochromocytoma is suspected. Treat the clinical emergency and organ injury, not the number alone.

Synopsis

Recognise, confirm and stage adult hypertension; identify same-day emergencies; start evidence-based treatment and monitor safely in UK practice.

  • Measure BP with the person seated, relaxed, arm supported and an appropriately sized cuff; check the pulse first and use manual auscultation if it is irregular.
  • Measure both arms initially. If the difference remains greater than 15 mmHg after repeat measurement, use the arm with the higher reading thereafter.
  • Clinic BP 140/90 to 179/119 mmHg should usually be confirmed by ABPM; use HBPM if ABPM is unsuitable or not tolerated.

Key red flags

Severe hypertension without emergency features

BP 180/120 mmHg or higher but no retinal haemorrhage/papilloedema and no life-threatening symptoms: promptly test for target-organ damage. If none is found, confirm with ABPM/HBPM or repeat clinic BP and complete clinical review within 7 days.

Investigation priorities

01
Repeat standardised clinic BP in both armsFirst step

Confirm the initial reading and identify an inter-arm difference.

02
ABPMPreferred

Preferred confirmation for clinic BP 140/90 to below 180/120 mmHg.

Management branches

NICE diagnosisConfirm and risk-stratify

Clinic BP 140/90 to below 180/120 mmHg without emergency features.

  1. Repeat clinic BP correctly, arrange ABPM or HBPM, and simultaneously investigate target-organ damage; do not wait for out-of-office confirmation before investigating.
  2. Document stage, standing BP where indicated, comorbidity, medicines/substances, family history, lifestyle and QRISK3.
NICE stepwise treatmentPreferred long-term medicines

Confirmed hypertension requiring pharmacological treatment.

Key medicines

RamiprilUsually 2.5 mg orally once daily; start 1.25 mg once daily with marked renin-angiotensin activation or relevant diuretic use, then double at 2–4-week intervals to a maximum 10 mg/day according to response and tolerance.
Losartan50 mg orally once daily; consider 25 mg once daily if intravascularly depleted, and increase to 100 mg once daily after response review, typically from about 1 month.
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Sources and review status12 sources · checked 25 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 25 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom