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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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CT coronary angiography

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Acute coronary syndrome is a clinical emergency pathway

Ongoing or recent high-risk chest pain, haemodynamic instability, acute ECG change or troponin evidence requires immediate acute coronary syndrome assessment; an elective CTCA request must not delay it.

Action: Escalate to the acute chest-pain pathway, obtain time-critical ECG and biomarker assessment, and use coronary CT only where the acute service judges it appropriate after immediate threats have been addressed.

Synopsis

Select, prepare, interpret and act on CT coronary angiography while separating coronary anatomy from ischaemic significance and recognising non-diagnostic or urgent findings.

  • CTCA is an anatomical test that shows coronary plaque, luminal narrowing, anomalous origins and selected extracoronary structures.
  • For stable typical or atypical angina without established coronary disease, NICE recommends 64-slice or higher CTCA as the diagnostic imaging test.
  • Good acquisition needs a stable rhythm, limited coronary motion, adequate contrast delivery and an appropriate radiation protocol tailored to the patient.

Key red flags

Current chest pain with haemodynamic instability, dynamic ischaemic ECG change or suspected myocardial infarction needs emergency assessment rather than routine CTCA preparation.

A suspected left main stenosis, severe multivessel disease or acute coronary occlusion on CTCA requires prompt direct communication and cardiology review.

A scan showing an important non-coronary emergency, such as acute aortic syndrome or major pulmonary embolic disease within the imaged field, must trigger immediate escalation.

Severe contrast reaction, sustained arrhythmia or clinical deterioration during acquisition requires stopping the examination and applying the department's emergency response.

Potentially obstructive disease

Focal or diffuse luminal narrowing should be described by artery, segment and severity. Anatomical importance rises with left main, proximal or multivessel involvement, but functional significance is not inferred from appearance alone when uncertainty remains.

Coronary anomalies and variants

Define origin, proximal course, dominance and any interarterial or intramural relationship. Clinical importance depends on the exact anatomy, symptoms and evidence of ischaemia, not merely the word anomaly.

Incidental extracoronary findings

Review the aorta, valves, pericardium, lungs and mediastinum within the reconstructed field. Report consequential abnormalities through an agreed pathway while avoiding overcalling benign findings from a limited cardiac acquisition.

Investigation priorities

01
CT coronary angiographyFirst step

Define coronary plaque, lumen, origins and course in a diagnostic-quality anatomical study.

Management branches

Stable chest pain pathwayChoose CTCA after clinical assessment

Recent-onset stable chest discomfort remains typical or atypical angina, or non-anginal pain has relevant resting ECG changes.

  1. Document pain typicality, cardiovascular history, risk factors, resting ECG and whether coronary disease is already established.
  2. Check renal function, previous contrast reaction, pregnancy possibility, rhythm, heart rate and ability to cooperate with breath holding.
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Sources and review status3 sources · checked 12 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 12 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom