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Principles of interventional radiology

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Deterioration around an image-guided procedure

Hypotension, hypoxia, reduced consciousness, severe pain, new neurological deficit or rapidly enlarging swelling may indicate haemorrhage, sepsis, contrast reaction, oversedation or target-organ injury.

Action: Stop the procedure or transfer, call for senior interventional and resuscitation support, use an ABCDE assessment, identify the likely procedural complication and obtain urgent imaging, blood products, antidote or definitive haemostasis as the physiology requires.

Synopsis

Understand how image-guided access, targeted therapy, procedural planning and structured aftercare allow interventional radiology to diagnose and treat disease while controlling bleeding, infection, radiation and organ-injury risks.

  • Interventional radiology uses ultrasound, fluoroscopy, CT or MRI to place a needle, wire, catheter or device accurately for diagnosis or treatment through a small access route.
  • The clinical question determines both the target and modality: ultrasound gives real-time soft-tissue and vascular guidance without ionising radiation, fluoroscopy follows wires and contrast dynamically, and CT maps deep structures and gas well.
  • The Seldinger sequence is needle entry, guidewire passage, needle removal, tract dilation and catheter or sheath placement; wire position must remain controlled throughout every exchange.

Key red flags

New haemodynamic instability, falling haemoglobin, abdominal or back pain, access-site expansion or loss of distal pulses after an intervention requires immediate assessment for occult bleeding or arterial injury.

Fever, rigors, hypotension or worsening organ dysfunction after drain or stent manipulation may represent bacteraemia or sepsis and needs cultures, antimicrobial treatment and source-control review.

Stridor, bronchospasm, facial or tongue swelling, hypoxia or shock after contrast or another procedural medicine is a resuscitation emergency.

New weakness, speech disturbance, visual loss or severe unexpected pain during a vascular procedure raises embolic or ischaemic injury and requires the procedure team to act immediately.

Route-specific risk

A transpleural route risks pneumothorax, a transhepatic route risks bleeding or bile leak, vascular access risks haematoma and distal ischaemia, and contaminated systems may seed infection; route planning predicts surveillance needs.

Reasoning priorities

01
Review of current cross-sectional and ultrasound imaging

Confirm the target, define anatomy and select a route with an acceptable risk-benefit balance.

Assess target size and visibility, intervening bowel or pleura, vessels, collateral supply, access options and signs that the referral question has changed since the scan.

Worked reasoning

Worked case: obstructed infected kidneyPlan image-guided decompression

A septic patient has hydronephrosis from an obstructing ureteric stone, thrombocytopenia, a distended collecting system on CT and no immediate endoscopic access.

  1. Identify urgent source control as the objective, resuscitate and give cause-appropriate antimicrobials while urology, radiology and anaesthesia agree that percutaneous nephrostomy is the practical decompression route.
  2. Review CT and bedside ultrasound for laterality, calyceal dilatation, retrorenal bowel and a feasible posterior calyx; assess platelets, coagulation, antithrombotics and cardiorespiratory tolerance without delaying life-saving drainage unnecessarily.
  3. Use aseptic technique, local anaesthesia and ultrasound-guided puncture, confirm collecting-system entry with urine and minimal contrast when appropriate, then maintain guidewire control while dilating and placing a locking drain.
  4. Aspirate a specimen for microbiology, secure and connect the catheter, document urine appearance and output, and give clear flushing, bag, escalation and replacement instructions.
  5. Verify decompression by clinical improvement and drain function; failure of urine output, worsening sepsis, bleeding or displacement prompts immediate tube and collecting-system assessment rather than assuming technical placement equals source control.
Elective planningConvert a referral into a procedure plan

A stable patient is referred for an image-guided diagnostic or therapeutic intervention.

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Sources and review status5 sources · checked 12 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 12 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom