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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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Cancer surveillance in colitis

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Symptoms suggesting obstruction, perforation or established cancer

Progressive distension with vomiting or obstipation, peritonism, severe pain, haemodynamic deterioration, a palpable mass, marked ongoing bleeding, new iron-deficiency anaemia or weight loss must not wait for a routine surveillance slot.

Action: Assess urgently according to physiology. Use ABCDE resuscitation for acute deterioration, obtain blood count, renal profile, CRP, lactate and blood-bank samples as indicated, and arrange urgent contrast CT with colorectal and gastroenterology review for obstruction, perforation or a suspected cancer. Surveillance recall is replaced by a diagnostic and treatment pathway.

Synopsis

Apply current BSG risk assessment and colonoscopic surveillance to colonic inflammatory bowel disease, use high-quality dysplasia detection, and route visible, invisible and unresectable lesions through an IBD dysplasia multidisciplinary team.

  • Offer baseline colonoscopic risk assessment around 8 years after symptom onset for colonic IBD, but do not place repeatedly confirmed isolated proctitis into an IBD surveillance programme; PSC instead triggers annual surveillance from diagnosis.
  • Current BSG risk strata use annual surveillance for moderate active inflammation, dysplasia, PSC or a colonic stricture, and every 3 years for mild activity, extensive colitis or post-inflammatory polyps.
  • People whose risk remains close to the general population enter population colorectal screening and receive colonoscopic risk reassessment every 10 years rather than automatic 1–3-year IBD surveillance.

Key red flags

Progressive distension with vomiting or obstipation, peritonism, severe pain or haemodynamic deterioration suggests obstruction or perforation and needs acute surgical assessment.

A new colonic stricture, mass, persistent bleeding, iron-deficiency anaemia or weight loss requires prompt cancer assessment rather than waiting for surveillance recall.

Invisible multifocal dysplasia, unresectable visible dysplasia or invasive cancer requires timely expert MDT and colorectal surgical discussion.

Investigation priorities

01
High-definition surveillance colonoscopyFirst step

Inspect the entire colitis-affected colon, update disease extent and inflammatory activity and detect visible dysplasia.

Management branches

Worked case: new PSC during long-standing colitisReset surveillance to the current high-risk interval

A 49-year-old has had extensive ulcerative colitis symptoms for 12 years. The last high-definition surveillance colonoscopy 20 months ago showed no dysplasia. Magnetic-resonance cholangiography now supports a new diagnosis of primary sclerosing cholangitis.

  1. Confirm the colitis history, prior histology, extent, preparation quality, family history and the new PSC diagnosis. Do not use the previously planned three-year interval because PSC now confers an annual-surveillance indication.
  2. Arrange high-definition surveillance colonoscopy now with experienced IBD surveillance practice and dye-based chromoendoscopy. Optimise current inflammation and bowel preparation without delaying for years.
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Sources and review status3 sources · checked 8 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 8 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom