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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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Colonoscopy, flexible sigmoidoscopy and CT colonography

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Suspected perforation or major post-procedure bleeding

Severe abdominal pain, peritonism, haemodynamic instability or suspected perforation after endoscopy or CT colonography requires urgent assessment rather than routine post-procedure advice.

Action: Stop oral intake, call senior endoscopy and colorectal teams, begin ABCDE care with intravenous access and blood tests, and obtain urgent contrast CT when safe; involve anaesthesia and proceed to antibiotics, radiological control or surgery according to perforation, bleeding and physiology.

Synopsis

Match colonoscopy, flexible sigmoidoscopy or CT colonography to the anatomical question, need for tissue or therapy, procedural risk and bowel-preparation feasibility, then close any incomplete examination.

  • Choose the test by anatomical reach, need for biopsy or therapy, patient fitness and preparation feasibility.
  • Colonoscopy examines mucosa throughout the colon and permits biopsy or polypectomy when complete and well prepared.
  • Flexible sigmoidoscopy assesses distal bowel only and cannot exclude right-sided disease.

Key red flags

Severe abdominal pain, peritonism, haemodynamic instability or suspected perforation after endoscopy or CT colonography requires urgent assessment rather than routine post-procedure advice.

Investigation priorities

01
ColonoscopyFirst step

directly inspect the whole colonic mucosa and obtain biopsy or provide endoscopic therapy

Management branches

Worked case: applied colonoscopy, flexible sigmoidoscopy and ct colonographyReach a specific decision and confirm it happened

A frail 79-year-old with iron-deficiency anaemia needs assessment of the whole colon. Previous sedation caused respiratory compromise, so the team must compare CT colonography with carefully planned colonoscopy and explain downstream biopsy needs.

  1. Define that the diagnostic target is the entire colon because iron-deficiency anaemia can arise from proximal disease; a flexible sigmoidoscopy would leave that target incompletely assessed.
  2. Review prior respiratory compromise, current fitness, renal function, bowel-preparation safety and whether likely lesions would require immediate biopsy or polypectomy.
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Sources and review status4 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom