Doctor’s Passport

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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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Outpatient versus inpatient management

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Failed home management or newly complicated disease

New hypotension, confusion, guarding, persistent vomiting, acute kidney injury, rising fever or uncontrolled pain after discharge requires immediate hospital reassessment for sepsis or a missed complication.

Action: Reassess ABCDE, obtain intravenous access and repeat blood tests and abdominal examination; give intravenous fluid and antibiotics when indicated, involve surgery and repeat CT if deterioration suggests perforation or abscess.

Synopsis

Select outpatient care only for physiologically stable uncomplicated diverticulitis with adequate oral intake, manageable pain, acceptable comorbidity and reliable review; admit sepsis, complication or inability to self-care.

  • Home treatment requires uncomplicated anatomy, stable physiology, controlled pain, adequate oral intake and a dependable route back to care.
  • For a systemically well person with uncomplicated disease, review the need for antibiotics and consider discharge without them.
  • Systemic illness, immune suppression or significant comorbidity favours antibiotics even when CT shows no abscess or perforation.

Key red flags

Peritonism, systolic hypotension, altered mental state or oliguria excludes routine outpatient care and requires urgent resuscitation.

Inability to retain fluids or oral medicines creates dehydration and treatment failure even when the original CT was uncomplicated.

Immune suppression, substantial frailty, major comorbidity or unreliable access to urgent review lowers the threshold for admission and antibiotics.

Reasoning priorities

01
Contrast CT where indicated

separate uncomplicated from complicated disease.

Abscess, free perforation, obstruction or fistula generally shifts care toward admission.

Worked reasoning

Worked case: safe outpatient management without antibioticsTest home-care criteria and confirm recovery

A 52-year-old has CT-confirmed uncomplicated sigmoid diverticulitis, temperature 37.1°C, pulse 78/min, blood pressure 128/74 mmHg, eGFR 88 mL/min/1.73 m² and pain controlled by oral analgesia. Fluids are tolerated and a partner can assist at home.

  1. Review CT explicitly for absence of abscess, free perforation, obstruction and fistula, and repeat the abdomen after analgesia to confirm there is no guarding.
  2. Check immune status, major comorbidity, cognition, mobility, oral intake, analgesic effect and the practical route for same-day reattendance.
  3. Because the patient is systemically well with uncomplicated disease, agree no antibiotic treatment and provide written hydration, diet and analgesia instructions.
  4. Book a telephone or face-to-face review in 48 hours and give immediate return triggers: fever, increasing constant pain, vomiting, distension, syncope or reduced urine.
  5. At review, temperature remains normal, pain has fallen from 6/10 to 2/10 and normal meals are tolerated; document recovery and investigate if the course later becomes atypical.

Key medicines

Co-amoxiclav intravenousNICE lists co-amoxiclav 1.2 g intravenously three times daily for suspected or confirmed complicated acute diverticulitis. If IV treatment is needed for another specific reason, such as vomiting that prevents oral therapy, select the dose from renal function: the current 1000/200 mg SmPC uses 1000/200 mg once then 500/100 mg twice daily when creatinine clearance is 10–30 mL/min.Check immediate penicillin or other beta-lactam hypersensitivity and previous co-amoxiclav jaundice, calculate creatinine clearance rather than relying on age or creatinine alone, review hepatic function, cultures and local resistance, ensure hydration and step down when oral treatment is tolerated.
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Sources and review status5 sources · checked 8 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 8 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom