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Basal-cell carcinoma

Essential points for quick revision.

Synopsis

Recognise nodular, superficial, morphoeic and pigmented basal-cell carcinoma, stratify anatomical and histological risk, refer appropriately and explain why apparently slow growth can still cause major local destruction.

  • Nodular BCC is a pearly or translucent papule with arborising vessels, rolled edge and possible central ulceration.
  • Superficial BCC is a thin pink-red, brown or subtly pigmented scaly plaque, often on trunk, and can resemble eczema.
  • Morphoeic BCC appears scar-like, firm, pale or yellow-white and poorly defined; its subclinical extension makes it high risk.

Key red flags

Rapid change, deep fixation, cranial-nerve symptoms, recurrent tumour, ill-defined morphoeic plaque, large neglected ulcer or periocular, nasal, lip or ear disease threatens critical structures and requires urgent specialist assessment.

Morphoeic scar-like plaque

An indurated ivory or yellow-white poorly defined plaque can extend well beyond what is visible.

Investigation priorities

01
DermoscopyFirst step

Identify arborising vessels, shiny white structures, ulceration, leaf-like areas and blue-grey nests.

Management branches

Low-risk suspected BCCObtain diagnosis and definitive care

A well-defined primary lesion is away from high-risk sites and lacks aggressive features.

  1. Document site, size, border and dermoscopy and refer through the local routine BCC pathway when clinically appropriate.
  2. Use standard excision with histology for many lesions or a selected non-surgical option for confirmed superficial low-risk disease.

Key medicines

Imiquimod 5% creamFor selected small superficial BCC, apply five times weekly for six weeks according to the licensed product and specialist-confirmed plan.
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Sources and review status3 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom