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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Candidal intertrigo

Dermatology · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull

Synopsis

Recognise Candida-associated fold inflammation, distinguish it from dermatophyte, bacterial and inflammatory mimics, correct moisture and friction, and use topical antifungal treatment while investigating recurrent disease selectively.

  • Candidal intertrigo is a sore, moist, confluent fold eruption with maceration, fissures and possible satellite papules or pustules.
  • Erythema may look red, violet, grey or dark brown across skin tones; gloss, erosion, tenderness and satellite morphology are often more reliable.
  • Reduce moisture and friction with gentle drying, breathable clothing, absorbent non-adherent material and management of sweat or incontinence.
  • Apply clotrimazole 1% cream thinly two or three times daily for at least two weeks according to the licensed product.
  • Avoid potent steroid–antifungal mixtures and prolonged fold steroid exposure; use a brief low-potency anti-inflammatory only for a defined indication.
  • Take fungal sampling for recurrent, atypical or treatment-resistant disease and bacterial culture when pus, odour, cellulitis or systemic illness suggests coinfection.
  • Check HbA1c when recurrence or symptoms suggest diabetes, but do not order broad immune testing for one ordinary episode.
  • Reconsider inverse psoriasis, erythrasma, tinea, contact dermatitis and flexural blistering disease when a correctly applied course fails.

Key red flags

Fever, rapidly spreading pain, crepitus, necrosis, perineal involvement, diabetic decompensation, severe immune compromise, extensive erosion or failure of a well-used regimen requires urgent or specialist reassessment.

Invasive-infection departure

Rapid spread, disproportionate pain, crepitus, necrosis, fever or shock is not uncomplicated intertrigo and needs emergency care.

Investigation priorities

01
Skin scraping or fungal swabFirst step

Confirm Candida or dermatophyte in recurrent, atypical or non-responsive disease.

Management branches

Typical uncomplicated diseaseDry and treat the fold

A local moist satellite-pustular fold eruption occurs without invasive infection or major immune compromise.

  1. Clean gently, pat completely dry, reduce friction and moisture and address incontinence or occlusive clothing.
  2. Apply clotrimazole 1% cream thinly two or three times daily for at least two weeks, extending to the affected margin.
  3. Review tolerance and response, continuing environmental measures after clearance and avoiding unneeded antibiotic or potent steroid combinations.

Key medicines

Clotrimazole 1% creamApply a thin layer two or three times daily to clean dry affected folds for at least two weeks according to response and product information.Avoid eyes and mucosa, stop for marked irritation or allergy, and recognise that some excipients can damage latex contraception or provoke contact dermatitis.
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Sources and review status3 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • NHS fungal skin infectionsCandida risk, topical treatment and recurrence assessment.
  • DermNet candidal intertrigoFold morphology, differential diagnosis and investigations.
  • Clotrimazole 1% cream SmPCApplication frequency, indication and cautions.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom