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RapidMLAMSRAGP

Hidradenitis suppurativa staging and care

Essential points for quick revision.

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Do not label spreading infection as an ordinary flare

Rapidly spreading erythema or colour change, disproportionate pain, crepitus, systemic toxicity or perineal necrosis suggests cellulitis, sepsis or necrotising infection beyond uncomplicated hidradenitis.

Action: Assess ABCDE, start the local sepsis pathway, obtain urgent surgical review for possible necrotising infection and give antimicrobials without delaying source control.

Synopsis

Diagnose hidradenitis suppurativa from recurrent lesions in typical flexures, stage structural damage, identify emergencies and comorbidity, and coordinate medical, wound, pain, lifestyle and surgical care without blame.

  • Diagnosis rests on typical lesions, typical flexural sites and chronic recurrence: painful nodules, abscesses, tunnels and scars in axillae, groins, inframammary, abdominal-fold, genital, perianal or buttock skin.
  • Ask whether there have been at least two episodes in six months, but do not let an arbitrary frequency erase a convincing longer recurrent history.
  • Hurley I has nodules or abscesses without tunnels and permanent scars; Hurley II has recurrent lesions with separated tunnels or scars; Hurley III has diffuse interconnected disease.

Key red flags

Sepsis physiology, rapidly progressive perineal pain, crepitus, urinary obstruction, uncontrolled bleeding, a chronic ulcer or mass suggesting squamous-cell carcinoma, severe depression or suicidal thoughts requires urgent escalation.

Necrotising-infection warning

Rapid perineal progression, disproportionate pain, crepitus, dusky necrosis, confusion or hypotension requires immediate surgical and sepsis management.

Investigation priorities

01
Full-site lesion map and Hurley stageFirst step

Document structural extent and identify areas needing medical or procedural treatment.

Management branches

Limited early diseaseReduce new inflammatory lesions

Hurley I or limited Hurley II disease has active nodules without an emergency or extensive tunnel field.

  1. Explain the diagnosis without hygiene blame, reduce friction and traumatic hair removal, offer absorbent non-adherent dressings and create a proportionate pain plan.
  2. Consider off-label topical clindamycin for localised disease or a twelve-week oral tetracycline for more widespread activity, using an explicit response and stop assessment.

Key medicines

Clindamycin 1% topical lotionApply a thin film twice daily to clean, dry affected areas for a defined trial according to the agreed off-label hidradenitis plan.
Lymecycline 408 mg capsulesTake one capsule orally once daily for an initial twelve-week off-label anti-inflammatory course, with a documented response and stop review.
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Sources and review status5 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom