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RapidMLAMSRAGP

Lichen planus

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Escalate

Rapid painful mucosal erosion causing dehydration, dysphagia, urinary obstruction, severe genital adhesion or ocular involvement requires urgent specialist assessment and supportive care.

Synopsis

Recognise cutaneous, mucosal, scalp, nail and pigmentary lichen planus, confirm atypical disease safely, protect scarring sites, and monitor persistent lesions for malignant change.

  • Classic cutaneous lichen planus is an itchy eruption of flat-topped shiny papules, often violaceous or darker than surrounding skin, with fine pale Wickham striae on wrists, ankles and lower back.
  • Examine mouth, genital skin, scalp and nails with explanation and consent: specialised-site disease can scar even when the ordinary skin eruption is modest.
  • In darker skin, papules may be deep brown or subtly purple, pale striae remain useful, and grey-brown post-inflammatory pigment can persist long after active inflammation.

Key red flags

A persistent indurated, ulcerated, bleeding or enlarging lesion within oral, genital or hypertrophic disease needs urgent biopsy assessment for squamous cell carcinoma.

Oral disease

Reticular white lacy lines may be asymptomatic, while erosive gingival or buccal disease is painful and affects eating. Examine the full mouth and palpate persistent ulcerated or indurated areas.

Investigation priorities

01
First-line complete skin and specialised-site examinationFirst stepFirst line

Map cutaneous, oral, genital, scalp and nail involvement and identify sites at risk of scarring or cancer.

Management branches

First-lineLimited cutaneous lichen planus

Typical skin papules without scarring-site disease, significant erosion or malignant warning features.

  1. Explain the often self-limiting course, avoid skin injury, use emollient or soap substitute for comfort, and document active papules separately from residual pigment.
  2. Observe asymptomatic limited disease; for itch or active inflammation, apply a prescribed potent or very potent topical corticosteroid carefully once daily to papules.

Key medicines

Clobetasol propionate 0.05% ointmentApply thinly to resistant cutaneous lichen planus once or twice daily for the shortest effective course, stopping or stepping down by 4 weeks; maximum 50 g weekly.
Emollient or soap substituteApply generously as often as needed to dry or itchy intact skin, smoothing rather than rubbing and separating from active topical medicine by about 20 to 30 minutes.
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Sources and review status5 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom