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Lichen simplex chronicus

Essential points for quick revision.

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Escalate

Urgently assess rapidly progressive pain, ulceration, purpura, systemic illness, severe genital symptoms, neurological deficit or a suspicious solitary plaque rather than attributing every symptom to habitual scratching.

Synopsis

Recognise lichenification as the product of repeated rubbing, identify the initiating itch and psychosocial amplifiers, and break the itch-scratch cycle without missing infection or malignancy.

  • Lichen simplex is a thick leathery plaque with exaggerated skin markings caused and maintained by repeated rubbing or scratching.
  • Common accessible sites include nape, forearms, ankles, lower legs, scalp and anogenital skin; one person may have several plaques.
  • Find the itch source: eczema, contact allergy, tinea, scabies, venous disease, neuropathy and systemic pruritus may initiate the cycle.

Key red flags

Non-healing ulcer, bleeding induration, widespread severe pruritus with systemic symptoms, genital scarring, neuropathic deficit, child safeguarding concern or treatment-resistant focal disease requires specialist evaluation.

Atypical tumour warning

Progressive induration, ulceration, bleeding or non-response despite verified treatment requires biopsy assessment.

Investigation priorities

01
Full skin, nail and mucosal examinationFirst step

Identify the primary itch disorder and other plaques beyond the presenting site.

Management branches

Typical focal plaqueInterrupt the itch-scratch cycle

A stable accessible lichenified plaque lacks infection, tumour features or a clear untreated mimic.

  1. Explain the reinforcement cycle, agree a non-shaming strategy such as short nails, covering at night and substituting pressure or cooling for scratching.
  2. Apply a potent topical corticosteroid thinly for a defined short course and use generous emollient to reduce dryness and friction.

Key medicines

Betamethasone valerate 0.1% creamApply thinly to an active body-site plaque once or twice daily for up to four weeks, then reduce or stop as skin flattens and itch settles.
Clobetasol propionate 0.05% ointmentAdults apply thinly once or twice daily only to severe resistant thick plaques under specialist direction, not exceeding four weeks or 50 g weekly.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom