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Seborrhoeic dermatitis

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Escalate

Escalate an unwell infant with generalised rash, fever, poor feeding or growth failure, and urgently assess an immunocompromised adult with extensive painful or infected disease rather than assuming routine seborrhoeic dermatitis.

Synopsis

Recognise infant and adult seborrhoeic dermatitis across skin tones, distinguish common mimics, use antifungal and anti-inflammatory treatment by site, and plan relapse prevention.

  • Adult seborrhoeic dermatitis affects scalp, eyebrows, nasolabial folds, ears and central chest with scale and erythema, lighter or darker change.
  • Cradle cap is usually self-limited and gently managed; an unwell infant, widespread eruption or growth failure needs paediatric assessment.
  • Ketoconazole shampoo reduces scalp Malassezia: use twice weekly for two to four weeks, leave three to five minutes, then once every one to two weeks for prevention.

Key red flags

Erythroderma, fever, failure to thrive, severe eye involvement, extensive disease with immunosuppression, neurological decline or treatment-resistant atypical plaques warrants broader assessment.

Kerion warning

Tender boggy scalp swelling, pustules, lymphadenopathy or hair loss suggests inflammatory tinea and risks permanent scarring.

Investigation priorities

01
Clinical distribution and scalp examinationFirst step

Confirm a sebaceous-zone pattern and look for hair-shaft or nail clues to alternatives.

Management branches

Adult scalp diseaseReduce scale and prevent recurrence

Dandruff or seborrhoeic scalp inflammation occurs without alopecia, kerion or systemic illness.

  1. Use ketoconazole 2% shampoo twice weekly for two to four weeks, massaging into wet scalp and leaving for three to five minutes before rinsing.
  2. Add a short site-appropriate anti-inflammatory scalp preparation when itch and inflammation remain prominent after scale control.

Key medicines

Ketoconazole 2% shampooAdults and adolescents wet hair and scalp, lather, leave for three to five minutes and rinse; use twice weekly for two to four weeks, then once every one to two weeks.
Ketoconazole 2% creamAdults apply to affected and immediately surrounding skin once or twice daily for two to four weeks; intermittent once-weekly maintenance may then be used.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom