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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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Adult resuscitation

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Suspected adult cardiac arrest

Unresponsiveness with absent or abnormal breathing, including agonal gasps, warrants immediate cardiac-arrest action.

Action: Call the emergency response, start CPR, attach an AED or manual defibrillator, and deliver an indicated shock without avoidable delay.

Synopsis

Deliver coordinated adult cardiac-arrest care by recognising arrest promptly, maintaining effective compressions and ventilation, treating the rhythm and reversible causes, and supporting recovery.

  • Call 999 immediately for an unresponsive person in the community, assessing breathing while the call connects.
  • Compress the lower half of the sternum at 100–120/min to a depth of 5–6 cm, allowing full recoil.
  • Use 30:2 until an effective tracheal tube or supraglottic airway permits continuous compressions with 10 breaths/min; return to 30:2 if supraglottic leakage prevents adequate ventilation.

Investigation priorities

01
Rhythm assessment during planned pausesFirst step

Select the electrical pathway with minimal interruption of compressions.

Management branches

Worked casePersisting ventricular fibrillation after three shocks

A monitored adult collapses into VF and remains pulseless despite three appropriately delivered shocks separated by two-minute CPR cycles.

  1. Resume compressions immediately after the third shock and check that pad placement, skin contact and delivered energy are appropriate; do not wait to inspect whether a pulse has appeared.
  2. Administer adrenaline 1 mg IV and amiodarone 300 mg IV while CPR continues, assigning one team member to record total shocks and administration times.

Key medicines

Adrenaline during adult cardiac arrestGive 1 mg IV promptly for a non-shockable rhythm or after the third shock for VF/pVT; repeat every 3–5 minutes while ALS continues. Use IO when suitable IV access cannot be rapidly obtained.This cardiac-arrest regimen must not be confused with the 500 microgram IM anaphylaxis regimen in a patient with a circulation. Record dose timing to avoid duplication.
Amiodarone for shock-refractory VF or pulseless VTGive 300 mg IV after three total shocks and a further 150 mg IV after five total shocks if VF/pVT persists or recurs during the arrest.Do not give it routinely for asystole or PEA. Drug administration must not defer the next required shock or interrupt effective chest compressions.
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Sources and review status3 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom