Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
2 min synopsisUK scopeSources checked 7 Sept 2026Clinical review pending
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Shock after significant injury
Hypotension, worsening consciousness or severe respiratory compromise after trauma may reflect concealed bleeding or a rapidly reversible thoracic threat.
Action: Activate the trauma response, control catastrophic external bleeding, support airway and breathing, activate major haemorrhage treatment where indicated and obtain immediate surgical assessment for definitive control.
Synopsis
Find and treat immediately lethal injuries, coordinate haemorrhage control and imaging, and prevent secondary injury during definitive-care transfer.
Control catastrophic haemorrhage at the start while the team assesses airway, breathing and circulation in parallel.
A normal initial haemoglobin does not exclude substantial acute blood loss; use physiology, mechanism and repeated measurements.
In hospital, active traumatic bleeding requires blood-product resuscitation rather than repeated crystalloid loading.
Investigation priorities
01
Blood gas, lactate and serial haemoglobinFirst step
Assess perfusion and follow the response to haemorrhage treatment.
Management branches
Worked casePelvic haemorrhage after a motorcycle collision
A rider has pelvic pain, cool peripheries, heart rate 132/min and systolic pressure 78 mmHg after a high-energy collision. There is no major external bleeding.
Activate the trauma and major-haemorrhage responses, support oxygenation and obtain large-bore access while checking for an immediately treatable thoracic cause.
Apply a purpose-made pelvic binder at the greater trochanters without repeatedly springing the pelvis. Immobilisation reduces movement; it does not establish that all bleeding is controlled.
Key medicines
Tranexamic acid for significant traumatic bleedingGive 1 g IV over 10 minutes as soon as possible within 3 hours of injury, followed by 1 g IV over 8 hours, using the adult major-haemorrhage regimen.Do not routinely start after 3 hours unless hyperfibrinolysis is demonstrated. Record earlier doses and avoid rapid injection. Severe renal impairment or prior thrombosis requires specialist assessment of the applicable product and clinical circumstances.
Blood components in active haemorrhageActivate the adult major-haemorrhage protocol; NICE recommends an initial plasma:red-cell ratio of 1:1, moving to laboratory-guided component replacement as soon as possible.Use correct emergency identification, warming and repeated assessment of ionised calcium, coagulation and temperature. Products cannot replace anatomical haemorrhage control; avoid automatic crystalloid substitution in hospital active bleeding.
National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.