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RapidMLAMSRAFoundation

Hypoglycaemia

Essential points for quick revision.

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Escalate

Treat a bedside glucose below 4.0 mmol/L in a hospital patient immediately. If consciousness, airway protection or swallowing is impaired, summon urgent help, use ABCDE, stop oral intake and follow the current JBDS-aligned local parenteral pathway. Do not delay treatment for venous confirmation, and investigate any failure to recover as possible persistent neuroglycopenia or another emergency.

Synopsis

Recognise and treat low glucose promptly while finding the cause, preventing recurrence and preserving essential background diabetes therapy safely.

  • Think ‘four is the floor’: a capillary reading below 4.0 mmol/L requires action in an adult inpatient even when symptoms are subtle or absent.
  • Choose treatment by consciousness and swallow safety, not by the number alone; oral carbohydrate is unsafe in a drowsy, fitting or uncooperative patient.
  • For a conscious cooperative adult, JBDS uses 15–20 g rapid-acting carbohydrate followed by a glucose recheck after 10–15 minutes and repeat treatment if still low.

Key red flags

Autonomic warning

Sweating, tremor, hunger, palpitations, tingling or anxiety may precede cognitive impairment and provide a window for self-treatment when swallowing remains safe.

Investigation priorities

01
Immediate capillary blood glucoseFirst step

Identify a reversible cause of acute behavioural, neurological or autonomic symptoms at the bedside.

Management branches

ConsciousTreat when swallowing is safe

Glucose is below 4.0 mmol/L and the adult is alert, cooperative and able to swallow safely.

  1. Give 15–20 g rapid-acting carbohydrate using a stocked option compatible with swallowing ability and any fluid or renal restriction, following the local JBDS-aligned chart.
  2. Recheck capillary glucose after 10–15 minutes; if it remains below 4.0 mmol/L, repeat the rapid treatment and reassess, using the escalation route if three cycles fail.

Key medicines

Rapid-acting oral carbohydrateGive 15–20 g of rapid-acting carbohydrate to a conscious cooperative adult, then recheck glucose after 10–15 minutes and repeat if it remains below 4.0 mmol/L, using the current local JBDS-aligned options.
Intravenous glucose for severe hypoglycaemiaJBDS lists 100 mL of 20% glucose over 15 minutes or 200 mL of 10% glucose over 15 minutes for an adult when intravenous treatment is required; prescribe the stocked concentration on the live local chart.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom