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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Abdominal ultrasound, CT, MRI, MRCP and ERCP

Gastroenterology and hepatology · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

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Escalate

Fever or sepsis with jaundice and biliary obstruction requires emergency drainage planning. After ERCP, new persistent epigastric pain, severe chest or abdominal pain, peritonism, haematemesis, melaena, falling haemoglobin or physiological deterioration may represent pancreatitis, perforation or bleeding and requires urgent imaging plus coordinated endoscopy, surgery and interventional-radiology review.

Synopsis

Select abdominal imaging by the anatomical and clinical question, understand contrast, radiation and MRI constraints, and reserve ERCP chiefly for biliary or pancreatic therapy with explicit prevention and recognition of complications.

  • Ultrasound is first-line for gallstones, biliary dilatation, ascites and many liver questions; it is dynamic and radiation-free but limited by bowel gas, body habitus and operator dependence.
  • Contrast-enhanced CT is fast and broad for acute abdomen, perforation, obstruction, ischaemia, bleeding, sepsis, trauma and cancer staging, but uses ionising radiation and often iodine.
  • MRI offers high soft-tissue contrast without ionising radiation; liver protocols and enterography answer focused questions but take longer and require implant, claustrophobia and motion assessment.
  • MRCP is a non-invasive, heavily fluid-sensitive MRI of bile and pancreatic ducts; it maps obstruction but cannot drain, extract a stone or obtain every required tissue sample.
  • ERCP is primarily therapeutic: sphincterotomy, stone extraction, stenting and drainage. Diagnostic uncertainty is usually addressed first with ultrasound, MRCP, EUS or CT.
  • In suspected common-bile-duct stones, NICE recommends liver blood tests and ultrasound, then MRCP when ducts are not cleared by ultrasound but are dilated or tests remain abnormal; consider EUS if MRCP is non-diagnostic.
  • Acute cholangitis with obstruction needs resuscitation, antibiotics and urgent drainage; waiting for elective MRCP can be unsafe in a deteriorating patient.
  • ERCP complications include pancreatitis, bleeding, infection, perforation and sedation injury; consent and a post-procedure escalation plan are mandatory.

Key red flags

Acute cholangitis

Fever or sepsis, right upper-quadrant pain, jaundice and cholestatic tests with obstruction suggest infected biliary pressure. Hypotension, confusion or organ dysfunction requires emergency drainage planning.

Acute abdomen needing CT

Peritonism, shock, pain out of proportion, obstruction, major gastrointestinal bleeding or postoperative deterioration usually requires prompt contrast CT protocolled to the suspected emergency.

Post-ERCP pancreatitis

New persistent epigastric pain radiating to the back with enzyme elevation and clinical pancreatitis after ERCP requires fluid, analgesic, severity and complication assessment.

Post-ERCP perforation or bleeding

Severe pain, subcutaneous emphysema, peritonism, tachycardia, fever, haematemesis, melaena or falling haemoglobin warrants urgent CT and endoscopy, surgery and interventional-radiology coordination.

Investigation priorities

01
Abdominal ultrasoundFirst step

Assess gallstones, bile-duct calibre, liver texture and lesions, portal or hepatic flow, kidneys, pelvic organs and ascites; guide safe aspiration or drainage.

Management branches

BiliaryJaundice or suspected duct stone

Cholestatic tests, jaundice, biliary pain or ductal concern prompts imaging.

  1. Assess for sepsis and organ dysfunction, obtain liver tests and ultrasound, and start urgent cholangitis treatment when clinically indicated.
  2. If ultrasound does not show a duct stone but the duct is dilated or liver tests remain abnormal, use MRCP; consider EUS if MRCP remains non-diagnostic and suspicion persists.
  3. Use ERCP for therapeutic duct clearance or drainage before or at definitive surgical management, according to stability and local expertise.
  4. Document stent removal or exchange and cholecystectomy planning so temporary treatment does not become permanent by omission.

Key medicines

Rectal diclofenac or indometacinA common adult prophylactic regimen is 100 mg rectally immediately before or after ERCP, chosen under the current BSG or local ERCP protocol.Avoid or seek specialist advice with NSAID hypersensitivity, active bleeding or ulceration, significant renal injury, relevant pregnancy stage or other contraindication. It does not eliminate pancreatitis risk.
Iodinated contrast mediumAgent, concentration, volume and injection rate are selected by radiology for body size, vascular access, examination and scanner protocol; there is no universal dose.Prior reactions, kidney risk and thyroid disease require assessment. Emergency benefit may outweigh theoretical renal risk; follow the local metformin and post-contrast policy rather than stopping it universally.
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Sources and review status6 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • NICE CG188: Gallstone diseaseUltrasound, MRCP, EUS and duct-clearance sequence.
  • BSG ERCP quality improvement standardsUK safe ERCP service, procedural and follow-up standards.
  • BSG guideline on sedation in GI endoscopyERCP sedation selection, high-risk assessment and monitoring.
  • RCR and RCEM statement on emergency contrast CTDo not delay clinically necessary emergency CT for routine renal checks.
  • MHRA gadolinium contrast safety adviceAgent-specific renal and vulnerable-population risk reduction.
  • RCR post-contrast AKI quality standardRisk assessment, renal testing and metformin context for planned CT.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. ·

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Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom