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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Colonic diverticular bleeding

Gastroenterology and hepatology · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
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Escalate

Ongoing bright or dark-red rectal bleeding with tachycardia, hypotension, syncope, chest pain, altered consciousness or poor perfusion is a major haemorrhage. Begin ABCDE care, activate the local major-haemorrhage pathway when indicated, obtain senior gastroenterology, colorectal, interventional-radiology and transfusion support, and use CT angiography promptly in haemodynamic instability. A brisk upper gastrointestinal source remains possible.

Synopsis

Stabilise acute haematochezia, recognise diverticular haemorrhage as a diagnosis requiring localisation and exclusion of alternatives, and coordinate endoscopic, radiological and antithrombotic decisions safely.

  • Diverticular bleeding is often abrupt, painless and substantial because a vasa recta adjacent to a diverticulum ruptures; many episodes stop spontaneously but recurrence is important.
  • Do not call bleeding diverticular simply because diverticula were seen previously. Cancer, angiodysplasia, ischaemic colitis, inflammatory disease, haemorrhoids and an upper-GI source need proportionate exclusion.
  • Judge physiology before estimating colour or volume: calculate shock index, repeat observations, assess perfusion and establish venous access while history is taken.
  • Haemoglobin can initially appear normal in acute blood loss, so serial values and clinical trajectory are more useful than a single reassuring result.
  • For haemodynamic instability or suspected active major bleeding, BSG guidance prioritises CT angiography because it rapidly localises arterial extravasation and directs embolisation.
  • A stable major lower-GI bleed generally requires admission and inpatient colonoscopy on the next available list after preparation; urgent unprepared colonoscopy is rarely effective.
  • Transfuse red cells using the current restrictive NICE and local major-haemorrhage strategy, individualised for active exsanguination and cardiovascular ischaemia.
  • Anticoagulant and antiplatelet interruption, reversal and restart must balance active haemostasis against the indication and thrombosis risk with the relevant specialist owner.

Key red flags

Typical diverticular haemorrhage

Abrupt painless passage of red or maroon blood, often with clots, in an older adult with diverticulosis is characteristic, but source attribution remains provisional until localisation or exclusion is adequate.

Haemodynamic major bleed

Syncope, tachycardia, hypotension, cool peripheries, oliguria, altered mentation or a shock index above the local instability threshold identifies high risk regardless of the initial haemoglobin.

Ischaemic or inflammatory bleed

Pain before blood, focal tenderness, fever or diarrhoea is atypical for uncomplicated diverticular haemorrhage and raises ischaemic colitis, infection, IBD or diverticulitis.

Upper gastrointestinal source

Melaena, haematemesis, raised urea relative to creatinine, liver disease, ulcer risk or haemodynamic instability with brisk haematochezia warrants parallel consideration of an upper source.

Investigation priorities

01
Serial observations and shock indexFirst step

Classify haemodynamic instability and response to resuscitation before selecting the diagnostic route.

Management branches

Unstable bleedingResuscitate and localise rapidly

Haematochezia accompanies shock, ongoing major loss or failure to respond durably to initial resuscitation.

  1. Begin ABCDE, two suitable venous lines, urgent bloods and crossmatch, warming, continuous observations and the local major-haemorrhage protocol when activation criteria are met.
  2. Call senior gastroenterology and colorectal teams, alert interventional radiology and transfusion services, and document last antithrombotic doses while analgesia and resuscitation continue.
  3. Arrange CT angiography promptly; if active extravasation is shown, proceed rapidly to catheter angiography and selective embolisation where available.
  4. If CTA is negative but instability continues, reassess for an upper source, intermittent bleeding and repeat or operative strategies through the multidisciplinary emergency team.
Stable major bleedPrepare for inpatient diagnosis and therapy

Bleeding is clinically major but haemodynamic stability is sustained after initial assessment.

  1. Admit, monitor stool and physiology, correct fluid and clinically important anaemia, and risk-assess comorbidity and antithrombotic indication.
  2. Undertake adequate bowel preparation with attention to aspiration, renal and fluid risks, then arrange colonoscopy on the next available appropriate list.

Key medicines

Red-cell transfusionUse the current NICE restrictive threshold and target for clinically significant bleeding, individualised during exsanguination or active myocardial ischaemia under the major-haemorrhage protocol.Avoid automatic liberal transfusion after bleeding stops. Monitor identity, reaction, volume overload, electrolytes and temperature, and pursue localisation and haemostasis simultaneously.
Anticoagulant reversalUse the agent-specific current hospital protocol only for life-threatening or uncontrolled bleeding after identifying the anticoagulant, last dose, renal function and indication.Reversal carries thrombosis risk and is not a substitute for source control. INR is inadequate for DOAC effect; involve haematology and the indication owner and document restart planning.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • BSG acute lower gastrointestinal bleeding guidelineRisk assessment, CTA, colonoscopy, embolisation, transfusion and antithrombotic principles.
  • NICE NG24 blood transfusionRestrictive red-cell strategy, reassessment and transfusion safety.
  • NICE NG147 diverticular diseaseContext for diverticular complications and referral when bleeding accompanies diverticular disease.
  • BSG antithrombotic endoscopy guidelineInterruption and resumption principles around acute GI haemorrhage and endoscopic intervention.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom
Treat a definite diverticular bleeding stigma using local endoscopic expertise and document whether attribution is definitive or presumptive.
  • Escalate recurrent instability to CTA and interventional radiology rather than repeating ineffective unprepared endoscopy.