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Colorectal polyps and polypectomy surveillance

Essential points for quick revision.

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Escalate

Severe abdominal pain, tachycardia, fever, peritonism or free gas after polypectomy suggests perforation or post-polypectomy electrocoagulation injury and needs urgent hospital assessment. Ongoing large-volume rectal bleeding, syncope or haemodynamic compromise requires acute lower-GI haemorrhage care, reversal planning and endoscopic, radiological or surgical haemostasis. A routine surveillance interval is irrelevant until the complication is stabilised.

Synopsis

Characterise colorectal polyps accurately, secure complete and safe excision, interpret pathology and procedural quality together, and apply UK post-polypectomy surveillance without unnecessary colonoscopy.

  • A polyp is a morphological finding, not a final diagnosis. Management depends on size, site, morphology, optical pattern, histology, number and confidence of complete removal.
  • Premalignant colorectal polyps include conventional adenomas and serrated lesions; small distal hyperplastic polyps generally carry different risk from proximal dysplastic serrated disease.
  • Suspected deep submucosal invasion should be photographed, described, biopsied selectively and referred for colorectal multidisciplinary planning rather than fragmented piecemeal removal.

Key red flags

Deep invasion signal

Ulceration, induration, convergence, depressed morphology, disrupted vascular pattern or convincing non-lifting raises submucosal cancer and should prevent casual piecemeal resection.

Investigation priorities

01
High-quality colonoscopyFirst step

Detect synchronous lesions, document caecal completion and bowel preparation, and permit complete optical characterisation and resection.

Management branches

At colonoscopyDescribe before removing

A colorectal polyp is identified during screening or symptomatic investigation.

  1. Record exact segment, calibrated size, morphology and optical pattern, photograph the lesion and inspect for synchronous disease before choosing treatment.
  2. Remove a lesion with an evidence-based technique within competence, retrieving tissue and documenting en-bloc versus piecemeal excision and confidence of completeness.

Key medicines

Bowel-cleansing preparationUse the locally selected split-dose regimen with timing matched to the procedure, adjusting formulation and fluid advice for kidney, cardiac and electrolyte risk.
Antithrombotic interruption planAlter aspirin, P2Y12 inhibitor, warfarin or direct oral anticoagulant only using the current BSG and local procedure-risk schedule for the individual's thrombotic indication.
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Sources and review status5 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom