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Impetigo, folliculitis and skin abscess

Essential points for quick revision.

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Deep, facial or systemic spread

Sepsis, rapidly progressive pain, orbital features, extensive necrosis, immune compromise or a deep abscess near critical structures requires urgent escalation.

Action: Use ABCDE if systemically unwell, obtain blood and deep pus cultures when indicated, start locally appropriate systemic therapy and involve surgery, ophthalmology or another anatomical specialist for immediate source control.

Synopsis

Distinguish superficial impetigo and folliculitis from a drainable abscess, use proportionate topical or oral therapy and manage recurrence, transmission and invasive complications.

  • Non-bullous impetigo causes thin-walled vesicles or pustules that rupture into characteristic golden or honey-coloured crusts.
  • Bullous impetigo produces flaccid fluid-filled blisters from toxin-producing Staphylococcus aureus and usually needs oral treatment.
  • Folliculitis is a superficial pustule centred on a hair follicle; many limited cases improve with hygiene and removal of friction or occlusion.

Key red flags

Pain out of proportion, bullae, anaesthesia, necrosis or crepitus suggests necrotising infection.

Drainable abscess

A tender fluctuant nodule with pointing, pus or an ultrasound-defined cavity indicates a collection needing incision and drainage.

Investigation priorities

01
Full skin and anatomical examinationFirst step

Define superficial versus deep disease, extent, drainable pus, lymphangitis and critical-site involvement.

Management branches

LOCAL IMPETIGOUse antiseptic before antibiotic

Non-bullous impetigo is localised and the patient is systemically well.

  1. Confirm the crusted superficial pattern and exclude herpes, eczema flare, ecthyma, cellulitis and bullous or widespread disease.
  2. Offer hydrogen peroxide 1% cream two or three times daily for five days when suitable and explain gentle crust cleansing and hand hygiene.

Key medicines

Hydrogen peroxide 1% creamApply a thin layer two or three times daily for five days to localised non-bullous impetigo when the preparation is suitable.
Fusidic acid 2% creamApply a thin layer three times daily for five days when localised non-bullous impetigo requires a topical antibiotic and antiseptic is unsuitable.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom