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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Acute compartment syndrome

Musculoskeletal medicine and orthopaedics · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
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Acute compartment syndrome is an immediate surgical emergency

Raised pressure within a closed myofascial space compromises muscle and nerve microcirculation; delay causes necrosis, contracture, rhabdomyolysis, renal failure, infection, amputation and death even while distal pulses remain palpable.

Action: Call a senior orthopaedic decision-maker immediately, release circumferential dressings and expose the limb, correct hypotension, elevate safely and reassess within 30 minutes, perform hourly documented examinations or concurrent pressure monitoring if findings are incomplete, and proceed to NCEPOD-1 decompression as soon as the diagnosis is made.

Synopsis

Recognise evolving compartment ischaemia from serial clinical change, release external pressure, use concurrent blood-pressure and compartment-pressure data when examination is uncertain, and achieve immediate complete decompression before irreversible injury.

  • Suspect acute compartment syndrome from the trajectory: worsening pain, passive-stretch pain, swelling, sensory change and analgesic escalation matter more than any single normal earlier examination.
  • Do not use palpable pulses to exclude it. Pulselessness is late or indicates a separate arterial emergency and should prompt simultaneous vascular and orthopaedic action.
  • BOASt requires hourly assessment of an at-risk patient, documenting time, mechanism, consciousness, neurology, circulation, pain, analgesic dose and response, interpretation and management rationale.
  • For symptoms or signs, split or remove circumferential dressings, expose and safely elevate the limb, correct systemic hypotension and re-evaluate within 30 minutes with senior review.
  • If clinical assessment is incomplete or inconclusive, measure every suspected compartment with concurrent blood pressure; a diastolic-minus-compartment pressure below 30 mmHg indicates increased risk.
  • An absolute compartment pressure above 40 mmHg supports considering urgent decompression, but a reassuring single reading does not overrule progressive clinical findings or exclude another compartment.
  • Once diagnosed, perform immediate open decompression of every involved compartment and excise non-viable muscle; lower-leg treatment generally uses a two-incision four-compartment fasciotomy.
  • Discuss the patient with plastic surgery within 24 hours and re-explore within 72 hours or earlier when indicated, leaving a documented plan for definitive soft-tissue management.

Key red flags

Increasing pain out of proportion to the injury, pain on passive stretch of muscles crossing the compartment, a tense swollen segment or rapidly rising opioid requirement requires immediate reassessment and escalation.

New paraesthesia, sensory loss or weakness indicates progressive nerve ischaemia; paralysis, pallor and absent pulses are late findings or suggest concurrent arterial injury and must never be awaited.

An obtunded, intubated, very young or cognitively impaired patient and a limb under dense regional blockade cannot report pain reliably, so objective surveillance and pressure measurement thresholds become particularly important.

Revascularisation, crush, high-energy tibial or forearm fracture, tight casts, bleeding disorders and prolonged limb compression create high-risk settings even when the initial examination was reassuring.

Investigation priorities

01
First-line serial clinical examinationFirst stepFirst line

Detect change early enough for limb-saving decompression.

Management branches

SuspectedRelease pressure and reassess

An at-risk limb develops disproportionate pain, passive-stretch pain, tension, analgesic escalation or neurological change.

  1. Contact senior orthopaedics immediately and record examination, time, analgesia, blood pressure and the change that triggered concern.
  2. Remove circumferential dressings to skin, correct hypotension, expose and position the limb safely and re-evaluate within 30 minutes.
  3. Continue hourly structured examination and obtain concurrent pressure monitoring when pain reporting or the clinical picture is incomplete.
  4. Maintain arterial surveillance and activate vascular care if perfusion remains abnormal after realignment or external pressure release.
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Sources and review status3 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • BOASt - Diagnosis and Management of Compartment Syndrome of the Extremities
  • NICE NG37 Fractures complex: assessment and management
  • BOASt - Diagnosis and management of arterial injuries associated with musculoskeletal trauma

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom