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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Delirium prevention after hip fracture

Musculoskeletal medicine and orthopaedics · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
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Acute behavioural change can signal deterioration

New reduced responsiveness, agitation, focal neurology, hypoxia, shock, hypoglycaemia, sepsis or opioid toxicity requires immediate physiological assessment before it is attributed to delirium.

Action: Use ABCDE, check bedside glucose and oxygenation, review medicines and pain, treat the time-critical cause and obtain urgent senior help for instability or new neurological findings.

Synopsis

Recognise hip-fracture patients at high delirium risk, deliver a coordinated multicomponent prevention bundle and detect hypoactive or fluctuating change early enough to treat causes.

  • Current hip fracture itself is a NICE delirium risk factor; age 65 or over, cognitive impairment and severe illness further increase vulnerability.
  • Record baseline cognition, function, communication and behaviour from the patient and someone who knows them before surgery whenever possible.
  • First-line diagnosis in most clinical settings is the 4AT after a recent change or fluctuation; use CAM-ICU or ICDSC in critical care or recovery.
  • Start a tailored multicomponent bundle within 24 hours: orientation, hydration, oxygenation, infection and constipation care, mobility, pain control, medication review, nutrition, sensory aids and sleep protection.
  • Use consistent staff and environment where feasible, visible clock and calendar, repeated explanation and family involvement; avoid unnecessary ward or room moves.
  • Give paracetamol 1 g orally every 6 hours before and after hip-fracture surgery unless contraindicated, reducing the dose for low weight, frailty, malnutrition or liver risk; add opioids cautiously and consider trained nerve block.
  • Do not use prophylactic antipsychotics or sedatives as a substitute for prevention; when delirium causes distress, treat causes and use verbal and non-verbal de-escalation first.
  • Mobilise with physiotherapy on the day after surgery unless medically or surgically contraindicated, and reassess daily for both hyperactive and hypoactive change.

Key red flags

A fall in consciousness, respiratory depression or pinpoint pupils after opioid administration may be toxicity and needs immediate airway and reversal assessment.

New focal weakness, unequal pupils, speech change, seizure or severe headache after the fall requires an acute neurological and head-injury pathway.

Hypotension, rising oxygen requirement, oliguria, fever or mottling suggests physiological deterioration or sepsis rather than uncomplicated postoperative confusion.

Severe agitation that creates immediate danger requires de-escalation, correction of causes and senior support; restraint or sedation can worsen harm.

Hypoactive delirium presents with withdrawal, slow responses, reduced movement and poor intake and carries serious risk despite appearing quiet.

Persistent cognitive change after acute causes settle needs follow-up for underlying dementia, depression or neurological disease without diagnosing chronic impairment during fluctuation.

Investigation priorities

01
First-line 4AT assessmentFirst stepFirst line

Evaluate alertness, orientation, attention and acute change or fluctuation when delirium indicators appear.

02
First-line physiological and bedside cause screenFirst line

Find hypoxia, hypoglycaemia, hypotension, fever, retention, constipation, pain and opioid excess immediately.

Management branches

AdmissionIdentify risk and baseline

An adult presents with hip fracture for operative or non-operative management.

  1. Record NICE risk factors and obtain baseline cognition, function, communication and behaviour from collateral sources.
  2. Assess pain, hydration, oxygenation, infection, retention, constipation, medicines, withdrawal and sensory needs.
  3. Place glasses, hearing aids, dentures, clock and orientation support within reach and avoid unnecessary transfers.
  4. Assign the tailored multicomponent prevention plan to the orthogeriatric and ward team within twenty-four hours.

Key medicines

Scheduled paracetamol for hip-fracture painGive 1 g orally every 6 hours before and after surgery unless contraindicated, using a lower dose or daily maximum for body weight below 50 kg, frailty, malnutrition or hepatic risk.Check all combination products and liver or alcohol risk; reassess severe pain for displacement, haematoma or another complication and do not exceed the individualised daily maximum.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • NICE CG103 Delirium RecommendationsRisk, multicomponent prevention, 4AT diagnosis, cause treatment and de-escalation.
  • NICE CG124 Hip Fracture RecommendationsAnalgesia, surgery, mobilisation and orthogeriatric delirium-aware care.
  • NICE QS16 Hip Fracture Quality StandardMultidisciplinary care, early rehabilitation and quality expectations after hip fracture.
  • MHRA Haloperidol Delirium Safety ReminderCardiac and neurological safety when short-term haloperidol is considered in older adults.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom