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Humeral-shaft fracture and radial-nerve injury

Essential points for quick revision.

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Open, vascular or progressive nerve injury

Most closed primary radial palsies recover, but open wounds, arterial compromise, penetrating trauma or a new deficit after manipulation can indicate laceration or entrapment needing urgent action.

Action: Perform ABCDE after high energy, cover open wounds and give intravenous prophylaxis within one hour, document pulses and named radial, median and ulnar functions, align and splint, and seek immediate orthopaedic, vascular or nerve input for tissue threat.

Synopsis

Stabilise humeral-shaft fracture, document radial and wider neurovascular function accurately, distinguish primary from new iatrogenic palsy, and select functional bracing, fixation or nerve exploration safely.

  • Inspect the whole arm for wounds, deformity and skin pressure and examine shoulder and elbow because associated joint injury changes care.
  • Before and after splintage, test wrist extension, finger MCP extension, thumb extension, dorsal first-web sensation, median and ulnar functions, pulses and refill.
  • Obtain AP and lateral radiographs of the full humerus including shoulder and elbow; pathological features may require staging before definitive fixation.

Key red flags

A cool hand, absent pulse, expanding arm haematoma or recurrent bleeding requires immediate realignment and combined vascular and orthopaedic assessment.

Shaft fracture

Arm pain, swelling, shortening, angulation and crepitus follow direct or torsional trauma.

Investigation priorities

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Full-length AP and lateral humeral radiographsFirst step

Define fracture and include both shoulder and elbow joints.

Management branches

First assessmentAlign and map nerve function

A humeral-shaft fracture is suspected after trauma.

  1. Use ABCDE for high energy, expose wounds and inspect shoulder, arm and elbow.
  2. Give analgesia and document pulses and radial, median and ulnar motor and sensory findings.

Key medicines

Paracetamol for adult arm-fracture painFor an adult, prescribe 500 mg to 1 g orally as required, with a minimum 4-hour interval and a maximum of four administrations in one day.
Intravenous prophylaxis for an open humerusGive the locally approved intravenous open-fracture agent and dose as soon as possible and within 1 hour, adjusted for allergy, renal function and contamination.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom