01OverviewDefinition, clinical context and the essential points that orientate the chapter.
Start with physiology and mechanism. Establish energy, crush or entrapment, contamination source, timing, first aid, water or farm exposure, tetanus history, anticoagulants, diabetes, vascular disease, smoking and baseline function. Control catastrophic bleeding before inspecting detail. Expose the whole limb and look for degloving and remote wounds. A pinhole can have been created from inside by a bone spike, so wound length cannot establish injury severity or communication.
The emergency examination is structured and repeated. Record dorsalis pedis, posterior tibial or relevant upper-limb pulses, Doppler signals, capillary refill, temperature and named peripheral nerve motor and sensory findings. Document compartments and active bleeding. Photograph once when governance permits. Remove only gross material that is sitting freely on the surface; do not probe, squeeze, repeatedly uncover or irrigate in the emergency department. Apply saline-soaked sterile gauze and an occlusive film.
Antibiotic timing matters more than inventing one universal drug. BOASt requires intravenous prophylaxis as soon as possible, ideally within one hour, and a readily accessible trauma-network regimen. Select agent and weight-based dose from that pathway because allergy, contamination, local resistance and renal function alter the prescription. Record all pre-hospital and referring-hospital doses so transfer does not create gaps. Assess tetanus risk and immunisation or immunoglobulin need using the current Green Book pathway.
Realignment reduces continued tissue injury and may restore perfusion. Provide analgesia, gently correct gross length and rotation and use a padded splint. Repeat circulation and nerve findings with the exact time. A deformed pulseless limb is realigned immediately; if pulse remains different from the other side, suspect arterial injury until CT angiography or exploration proves otherwise. Uncontrolled haemorrhage or a still-ischaemic limb needs emergency revascularisation and should not wait for routine imaging.
Initial classification is descriptive. Record wound position and approximate size, contamination, crush, skin loss, muscle viability, exposed bone, degloving and neurovascular findings. Gustilo type I describes a small low-energy wound with limited damage; type II is larger without extensive stripping; type III reflects high-energy or extensive tissue damage. IIIA has adequate cover after debridement, IIIB requires flap reconstruction for exposed bone, and IIIC has an arterial injury requiring repair. Reliable grading follows debridement, not a brief resuscitation-room view.
Formal debridement is a systematic operation led jointly by orthopaedic and plastic surgeons for injuries in BOASt scope. Extend through planned fasciotomy or reconstructive incisions, remove contamination and excise non-viable skin, fat, fascia, muscle and bone while preserving useful perfused structures. Muscle assessment uses colour, consistency, contractility and bleeding in context. Take deep microbiology only when clinically indicated by the operative pathway; routine pre-debridement wound swabs do not define prophylaxis.
Timing reflects biology. Debride immediately for highly contaminated agricultural, aquatic or sewage wounds and for vascular compromise from ischaemia or compartment syndrome. Other solitary high-energy injuries undergo debridement within twelve hours, and other low-energy injuries within twenty-four. After debridement, change instruments and re-prepare and drape before a clean fixation or reconstructive phase. Stabilisation restores length and enables care, but definitive internal fixation should coincide with definitive cover.
Close or cover definitively during debridement when suitable, otherwise within seventy-two hours. Coordinate fixation, recipient vessels, flap choice and incision position from the outset. If salvage versus delayed primary amputation is uncertain, involve orthopaedic and plastic surgeons, rehabilitation, the patient and family; a delayed primary amputation, when chosen, should occur within seventy-two hours. Discharge planning includes wound and flap surveillance, weight bearing, union imaging, antibiotics only for a defined indication, smoking cessation and rehabilitation.
Key points
- Treat any wound in the same segment as a fracture as communicating until careful operative assessment establishes otherwise; visible bone is not required.
- Control haemorrhage with direct pressure, packing or the most distal effective tourniquet and never apply blind clamps inside the wound.
- Give the network's intravenous prophylactic antibiotic as soon as possible and ideally within one hour; record agent, weight-based dose, allergy check and exact time.
- Handle the wound only to remove gross loose contamination and obtain one policy-compliant photograph, then apply saline-soaked gauze and occlusive film; emergency-department mini-washouts are not indicated.
- Gently restore gross alignment, splint and repeat named neurovascular examination. Persistent dysvascularity after realignment activates immediate consultant-led revascularisation rather than serial observation.
- Describe size, site, contamination, tissue loss, degloving, circulation and neurology initially. Assign the definitive Gustilo-Anderson grade after formal debridement reveals the true soft-tissue injury.
- Debride immediately for agricultural, aquatic or sewage contamination or vascular compromise; within 12 hours for other solitary high-energy injuries; within 24 hours for other low-energy open fractures.
- Achieve definitive closure or cover at debridement where possible or within 72 hours; perform definitive internal fixation only when immediate definitive soft-tissue cover can follow.
02AetiologyUnderlying causes, associations and risk factors, with why each one matters.
Outside-in penetration
Road trauma, crush, machinery and sharp objects drive contamination and foreign material through skin into the fracture and surrounding tissue.
Inside-out puncture
A sharp bone end can pierce skin during displacement and leave a deceptively small wound with a deeper communicating tract.
Ballistic and blast trauma
Projectiles and blast create variable cavitation, devitalisation, contamination and neurovascular injury extending beyond the visible entry wound.
Fragile skin failure
Low-energy fractures in older, steroid-exposed or chronically swollen limbs can open through thin compromised skin and still carry substantial infection risk.
03PathophysiologyThe causal sequence from the underlying abnormality to symptoms and harm.
- 1Bacterial inoculation
Communication introduces environmental and skin organisms into haematoma and bone, where devascularised tissue and implants can support biofilm and deep infection.
- 2Soft-tissue devitalisation
Crush, degloving and vascular disruption destroy local perfusion beyond the apparent wound edge, impairing antibiotic delivery, immunity, union and coverage.
- 3Periosteal and bone injury
Stripped periosteum and missing or contaminated bone reduce biological healing while unstable fragments perpetuate tissue trauma and dead space.
- 4Progressive swelling
Bleeding, inflammation and reperfusion raise tissue pressure and can enlarge necrosis, blistering and compartment compromise after the first inspection.
- 5Biofilm formation
Persistent organisms adhere to dead bone and fixation surfaces, becoming tolerant to host defence and antibiotics and causing fracture-related infection or nonunion.
04Clinical features and red flagsSymptoms, examination findings, patterns of presentation and time-critical warnings.
A puncture over the injured segment with fat globules, bleeding or a plausible bone-spike trajectory is an open fracture despite minimal surface damage.
Crush, degloving, contamination, periosteal stripping and muscle damage indicate severe biology even if temporary alignment makes the radiograph look simple.
After complete debridement, remaining viable local tissue can cover the exposed bone despite a high-energy or extensively contaminated injury.
Loss or devitalisation leaves bone exposed and requires flap coverage after debridement, irrespective of the initial wound measurement.
An associated arterial injury requiring repair defines IIIC severity regardless of wound size, fracture comminution or eventual method of coverage.
Progressive pain, passive-stretch pain, tension or neurological change requires full compartment assessment because an external opening provides unreliable decompression.
05InvestigationsWhat to request, why it matters and how to interpret it.
Read from the initial assessment onwards. Tests may run in parallel in urgent care; first-line, preferred, confirmatory, definitive and gold-standard labels appear only when the chapter explicitly states them.
- 01
First-line orthogonal fracture radiographsFirst stepFirst line - Why
- Define the fracture and joint extension while the limb is protected.
- Interpretation and limitations
- Image the whole injured bone and adjacent joints after emergency alignment when possible; foreign material, gas and bone loss add operative information.
- 02
Serial named neurovascular examination - Why
- Detect arterial, nerve and compartment deterioration before and after intervention.
- Interpretation and limitations
- Record pulse comparison, Doppler, perfusion and individual nerve modalities before and after realignment, splintage, transfer, debridement and fixation.
- 03
CT for articular and complex anatomy - Why
- Map fragments and joint extension for coordinated fixation.
- Interpretation and limitations
- Use after urgent alignment and without delaying antibiotic, haemorrhage, ischaemia or compartment treatment; integrate extremity sequences into trauma CT when indicated.
- 04
CT angiography - Why
- Define suspected arterial injury in a limb that remains sufficiently perfused for imaging.
- Interpretation and limitations
- Obtain urgently after realignment for pulse asymmetry or concerning trajectory; uncontrolled bleeding and persistent ischaemia go directly to consultant-led operative care.
- 05
Operative viability assessment - Why
- Establish true contamination and tissue loss and permit definitive grading.
- Interpretation and limitations
- Classification and reconstruction planning are revised after all non-viable tissue is excised and bone-cover requirements become clear.
- 06
Targeted trauma blood tests - Why
- Prepare for haemorrhage, anaesthesia and renal-safe medicines.
- Interpretation and limitations
- Use FBC, renal profile, coagulation, fibrinogen, group and screen or crossmatch and blood gas according to physiology without delaying antibiotics or limb-saving surgery.
- 07
Tetanus risk assessment - Why
- Determine vaccine and human tetanus immunoglobulin requirements.
- Interpretation and limitations
- Use wound contamination and reliable immunisation history under current UK guidance; antibiotics for fracture infection prophylaxis do not substitute for tetanus prevention.
06Differential diagnosisRealistic alternatives and the features that help distinguish them.
Closed fracture with superficial abrasion
A wound that does not communicate may be superficial, but this cannot be assumed from size or location without formal specialist assessment.
Traumatic arthrotomy
A peri-articular wound can enter the joint without an obvious fracture and still needs urgent washout and infection prevention.
Morel-Lavallée lesion
Closed internal degloving creates a fluctuant blood and lymph cavity with skin-perfusion and infection risk despite an intact surface.
Penetrating soft-tissue injury
A deep wound may damage tendon, nerve or vessel without fracture and requires the same deliberate structural and contamination examination.
Established fracture-related infection
A draining sinus, chronic nonunion or late implant exposure represents infection rather than a newly contaminated acute fracture pathway.
07ManagementImmediate care, first-line treatment, alternatives and escalation.
01ArrivalPrevent added contaminationFirst stepA fracture has any potentially communicating wound or major soft-tissue violation.+
- 1Run ABCDE, control bleeding without blind clamping and document the entire limb, compartments, pulses and named nerves.
- 2Give network intravenous prophylaxis ideally within one hour and assess tetanus needs without waiting for radiographs.
- 3Photograph once, remove only gross loose debris, apply saline-soaked gauze and occlusive film and stop repeated wound handling.
- 4Realign and splint, repeat neurovascular findings and activate orthoplastic and vascular transfer pathways according to injury.
02TheatreExcise dead tissue and stabiliseThe patient reaches the time-appropriate orthoplastic operating pathway.+
- 1Debride immediately for severe contamination or vascular compromise, within 12 hours for other high-energy and within 24 hours for other low-energy injury.
- 2Extend through reconstructively sound incisions, inspect all tissue layers, excise non-viable tissue and revise the grade after debridement.
- 3Change instruments, re-prepare and re-drape before treating subsequent fixation and coverage as a clean phase.
- 4DefinitiveUse temporary stability when definitive cover cannot follow and coordinate immediate internal fixation with definitive tissue cover.
03ReconstructionClose biology and function togetherDebridement defines a viable wound, bone defect and reconstructive requirement.+
- 1DefinitiveComplete definitive closure or flap cover at debridement or within 72 hours, protecting planned recipient vessels and fixation.
- 2Review perfusion, flap or graft, compartments, infection, union and alignment under a combined orthoplastic schedule.
- 3Make any salvage or amputation decision through multidisciplinary discussion with rehabilitation and informed patient or family involvement.
- 4Provide precise loading, wound, smoking, nutrition, pain, psychological and return-to-work rehabilitation instructions.
Key medicines and prescribing safety1 treatment · regimens, roles and cautions+
Immediate intravenous open-fracture prophylaxis
Give the trauma network's specified intravenous agent at its current adult weight-based dose as soon as possible and ideally within 1 hour of injury; record allergy, agent, dose and time and repeat only at the protocol-defined interval.No single national agent fits every allergy, renal function, local resistance pattern and agricultural, aquatic or sewage exposure; transfer must not delay the first appropriate dose, and prophylaxis must not drift into indefinite unreviewed treatment.
08ComplicationsImportant consequences, why they occur and why they matter clinically.
Fracture-related infection
Contamination, dead tissue, delayed cover and unstable biology can cause deep infection, osteomyelitis, sinus formation, implant failure and repeated reconstruction.
Delayed union and nonunion
Bone loss, periosteal stripping, infection, smoking and instability prevent bridging and prolong pain, disability and additional surgery.
Flap or skin failure
Poorly perfused tissue, swelling and uncoordinated incisions can cause necrosis, exposed fixation and loss of reconstructive options.
Compartment and vascular injury
Swelling or arterial damage can produce ischaemic muscle and nerve loss even when the external wound appears to vent pressure.
Amputation and chronic disability
Unsalvageable perfusion, uncontrolled infection or extensive tissue loss may require amputation, followed by pain, prosthetic and psychological rehabilitation.
09Monitoring and follow-upTreatment response, safety checks and longer-term review.
- Record every antibiotic agent, dose and administration time across pre-hospital, referring, transfer and theatre settings and correct a missed interval promptly.
- Repeat pulse comparison, Doppler, perfusion, named nerve and compartment findings after alignment, splintage, transfer, surgery and any pain or swelling change.
- Inspect skin, wound, fixation, pin sites and flap or graft through the agreed orthoplastic schedule, escalating necrosis, congestion, drainage, fever or unexpected pain.
- Track inflammatory and microbiological findings only in clinical context; superficial swab growth does not define deep fracture-related infection.
- Use serial radiographs and examination to follow alignment, bone defect, implant stability and union before advancing load or reconstructive stages.
- Review pain, sleep, smoking, nutrition, joint movement, strength, gait or hand function, work goals and psychological adjustment throughout recovery.
10Special situationsVariants, exceptions and circumstances that change the usual approach.
Grade after debridement
The full extent of stripping and viable cover becomes visible only after contamination and dead tissue are removed in theatre.
A wound can be distant
Bone can travel beneath skin before puncturing it, so communication is not excluded because the opening is away from the fracture line.
Open does not mean decompressed
Only the compartment breached by a sufficiently large fascial opening might vent, while other compartments can remain critically pressurised.
Coverage shapes fixation
Incisions, recipient vessels and flap need planning before implants occupy reconstructive corridors or compromise remaining blood supply.
Clean phase requires a reset
Fresh instruments and renewed preparation after debridement reduce transfer of contamination into fixation and definitive coverage.
Scores do not decide salvage
Physiology, perfusion, tissue, nerve, infection risk, function and patient priorities outweigh an isolated limb-severity score.
11Common pitfallsFrequent interpretation and management errors.
- 01
Calling a pinhole wound superficial because no bone is visible or the radiograph shows little displacement.
- 02
Delaying the first antibiotic dose until imaging, transfer, grading or arrival in theatre.
- 03
Performing an emergency-department mini-washout, repeated probing or repeated photography that adds contamination and tissue trauma.
- 04
Assigning a definitive Gustilo grade before debridement exposes the actual muscle, periosteal and coverage injury.
- 05
Performing internal fixation without a plan for immediate definitive soft-tissue cover.
- 06
Using antibiotics as a substitute for timely excision, stable fixation, dead-space control and viable closure.