Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
2 min synopsisUK scopeSources checked 27 Aug 2026Clinical review pending
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Escalate
Treat the current injury first: use ABCDE after significant trauma, give analgesia, document skin and distal neurovascular status, immobilise or protect weight bearing, and obtain urgent orthopaedic assessment for displaced hip fracture, threatened skin, open fracture, neurological deficit or suspected unstable vertebral injury. New weakness, saddle sensory change or bladder or bowel dysfunction requires the emergency spinal-compression pathway rather than routine osteoporosis review.
Synopsis
Recognise a fragility fracture as both an acute mechanical injury and a sentinel event, then combine safe orthopaedic treatment with prompt investigation and secondary fracture prevention.
A fragility fracture follows force no greater than a fall from standing height and is a treatment trigger, not a reason to postpone prevention until DXA.
First-line orthopaedic assessment addresses the current fracture: mechanism, pre-injury function, pain, skin, distal neurovascular status, imaging in two planes and safe loading instructions.
Use FRAX for ten-year probability and add femoral-neck DXA when the result will alter treatment; a recent hip or vertebral fracture already establishes high risk.
Key red flags
A painful deformed limb, inability to bear weight after trivial trauma or focal bony tenderness in an older adult may be a fracture even when bruising is slight.
Investigation priorities
01
First-line fracture radiographsFirst stepFirst line
Define location, displacement, articular involvement, bone texture and any destructive feature before loading or reduction decisions.
Management branches
ImmediateProtect and define the fracture
A low-energy injury produces focal pain, deformity or loss of weight-bearing ability.
Use ABCDE when indicated, provide analgesia and document skin, compartments and distal neurovascular findings.
Immobilise the painful region and restrict loading until radiographs and orthopaedic review establish stability.
Key medicines
Alendronic acid first-line oral antiresorptiveUse 70 mg orally once weekly, swallowed after an overnight fast with plain water while upright; wait at least 30 minutes before food, drink, other medicine or lying down.
Zoledronic acid after fragility fractureGive 5 mg by intravenous infusion no faster than 15 minutes, usually once yearly, only after confirming hydration, creatinine clearance, corrected calcium and adequate vitamin-D and calcium provision.
National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.