Skip to textbook content
Doctor’s PassportTextbook
TopicsAll topics

Loading topic navigation…

Textbook navigation
TopicsAll topics

Loading topic navigation…

Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Perthes disease

Musculoskeletal medicine and orthopaedics · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
!
Escalate

Perthes disease itself usually follows a gradual course, but a febrile child with acute severe hip pain, systemic illness or refusal to move the joint has septic arthritis until assessed urgently. Sudden inability to bear weight also requires fracture and SUFE exclusion. Do not force a stiff painful hip into abduction; provide analgesia, reduce impact and arrange timely paediatric orthopaedic imaging.

Synopsis

Recognise childhood femoral-head osteonecrosis, preserve hip motion and containment during biological fragmentation and select reconstruction by age, head involvement and mechanical congruence.

  • Perthes disease is idiopathic osteonecrosis of the capital femoral epiphysis, classically presenting between four and eight years with limp and hip, thigh or knee pain.
  • High-yield examination shows reduced hip abduction and internal rotation, an antalgic or Trendelenburg gait and possible thigh wasting.
  • First-line imaging is bilateral AP pelvis and frog-leg lateral radiography; obtain MRI when early disease remains suspected despite normal films.
  • Waldenström evolution moves through initial necrosis, fragmentation, reossification and healed remodelling over several years.
  • Lateral-pillar height during fragmentation, age at onset, range and femoral-head containment are central prognostic variables.
  • First-line treatment in a younger child with maintained containment is education, temporary impact reduction, analgesia and active restoration of abduction and rotation.
  • Use protected loading for painful fragmentation, but avoid prolonged indiscriminate immobilisation that worsens stiffness and deconditioning.
  • Older age, substantial lateral-pillar collapse or extrusion may justify femoral or pelvic containment surgery before fixed hinge abduction develops.

Key red flags

Fever, severe rest pain, systemic illness or marked inflammatory response is not typical Perthes disease and requires emergency infection assessment.

An older or obese adolescent with obligatory external rotation has possible SUFE rather than Perthes and must be made non-weight-bearing immediately.

Progressive loss of abduction or internal rotation allows extrusion and deformation and should prompt earlier specialist reassessment.

A head that hinges rather than enters the acetabulum during abduction should not be forced into containment treatment.

Bilateral symmetrical epiphyseal change or disproportionate short stature suggests skeletal dysplasia, endocrine disease or another systemic disorder.

Persistent limp after presumed transient synovitis needs repeat examination and imaging because early Perthes radiographs can initially appear normal.

Investigation priorities

01
First-line bilateral AP pelvis radiographFirst stepFirst line

Identify epiphyseal density, collapse, extrusion, acetabular coverage and bilateral or alternative disease.

Management branches

SuspectImage the persistent childhood limp

A young child has ongoing limp, referred knee pain or loss of abduction and internal rotation.

  1. Assess fever, systemic state, weight-bearing ability and red flags before performing gentle bilateral hip examination.
  2. Obtain AP pelvis and safe frog-leg lateral views of both hips and review previous transient-synovitis episodes.
  3. Use MRI when radiographs are normal but compatible restriction or limp persists.
  4. Refer confirmed or strongly suspected disease to paediatric orthopaedics for stage and containment assessment.

Key medicines

Ibuprofen for painful inflammatory phasesUse the current BNFC age- and weight-specific oral dose for a short course with food when the child is hydrated and has no renal, gastrointestinal or NSAID-sensitive asthma contraindication.Check weight and liquid strength, avoid dehydration and kidney disease and do not use analgesia to justify painful impact or forced range.
Paracetamol as alternative or adjunctPrescribe the BNFC dose for the child's age and weight with the exact formulation volume, interval and 24-hour maximum recorded for carers.Check combination products and liver risk; renewed night pain, fever or inability to bear weight requires reassessment rather than repeated dosing.
Open full textbook →Answer 2 questions
Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • Legg-Calve-Perthes Disease OverviewClinical pattern, staging, prognosis and treatment options.
  • NICE CKS Limp in ChildrenUK red flags, initial assessment and referral pathway.
  • POSNA Perthes Study GuidePaediatric orthopaedic staging, containment and outcomes.
  • BSCOS Public ResourcesUK children's orthopaedic information and specialist context.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom