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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
RapidMLAMSRAMRCSFoundation

Total hip and knee replacement indications

Essential points for quick revision.

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Elective replacement pauses when an active threat is present

Active joint or remote infection, uncontrolled medical instability, acute fracture, severe skin compromise or an undiagnosed rapidly destructive joint changes the timing and sometimes the operation.

Action: Identify and treat sepsis, fracture, vascular or medical instability first; investigate unexplained rapid destruction and optimise active infection, skin, diabetes, anaemia and medicines through a named pathway while maintaining proportionate access to arthroplasty assessment.

Synopsis

Make referral and operative decisions from quality-of-life impact, failed or unsuitable non-operative care, anatomy, goals and individual risk; explain implant choices and optimisation without inequitable numerical or demographic barriers.

  • Refer when joint pain, stiffness, deformity or reduced function substantially affects quality of life and non-surgical management is ineffective or unsuitable.
  • Use clinical assessment and shared decision-making; do not require a numerical severity score and do not exclude referral solely because of age, sex, smoking, comorbidity, overweight or obesity.
  • Confirm that symptoms arise from the target joint and that reasonable education, exercise, weight support and safe medication have been offered or are unsuitable; this is not a rigid checklist that prolongs avoidable disability.

Key red flags

A hot joint, draining sinus, persistent wound or unexplained raised inflammatory markers requires infection investigation before primary implantation.

Investigation priorities

01
Clinical indication assessmentFirst step

Measure symptom impact, goals and response or unsuitability of non-operative care.

Management branches

ReferBase referral on impact

Symptoms substantially affect quality of life and evidence-based non-operative care is ineffective or unsuitable.

  1. Confirm the likely pain-generating joint and document function, goals and previous treatment.
  2. Discuss replacement and continued non-operative options and refer without a numerical-score or demographic barrier.

Key medicines

Perioperative antimicrobial prophylaxisGive the hospital's current primary hip or knee replacement prophylactic antibiotic at the full weight-, allergy- and renal-adjusted dose within the protocol time before incision, record administration, and repeat intra-operatively only when the specific protocol duration or blood-loss criterion is met.
Venous-thromboembolism prophylaxisPrescribe the exact mechanical and pharmacological regimen from the current hospital elective-arthroplasty and NICE pathway, starting and continuing at the procedure-specific times after balancing thrombosis, neuraxial and bleeding risk.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom