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Functional neurological disorder

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Escalate

Functional neurological disorder can coexist with stroke, epilepsy, sepsis, cord compression and other emergencies. New unilateral weakness, first prolonged seizure-like event, acute visual loss, cauda-equina symptoms or significant injury still requires the appropriate time-critical assessment. A previous FND diagnosis must never be used as a shortcut to dismiss a new presentation.

Synopsis

Make a positive rule-in diagnosis of functional weakness, movement, sensory or seizure symptoms, communicate it without stigma, identify comorbid neurological disease, and organise rehabilitation around retraining and self-management.

  • Functional neurological disorder causes genuine motor, sensory, seizure, speech, gait or cognitive symptoms arising from altered nervous-system functioning rather than deliberate production.
  • Diagnosis is positively supported by internal inconsistency and preserved automatic function, not by normal scans, psychiatric history, unusual affect or failure to find another disease.
  • Hoover sign shows weak voluntary hip extension that improves when the opposite hip flexes against resistance, demonstrating preserved automatic motor recruitment.

Key red flags

Organic emergency overlap

Persistent aphasia, true vascular field loss, new sphincter dysfunction, fever or objective progressive neurology requires urgent disease-specific assessment despite known FND.

Investigation priorities

01
Positive neurological examinationFirst step

Demonstrate inconsistency and preserved automatic motor capacity.

Management branches

Acute presentationExclude emergency then seek positive signs

New weakness, abnormal movement, gait or seizure-like activity presents urgently.

  1. Use the standard stroke, seizure, cord, metabolic or injury assessment appropriate to onset and objective findings, without allowing a previous FND label to lower safety.
  2. Once immediate threats are addressed, test validated inconsistency signs and document exactly what changes with automatic movement, distraction or entrainment.

Key medicines

No core FND medicineThere is no medicine dose that directly corrects functional motor or seizure mechanisms; prescribe only for a defined comorbid symptom or diagnosis.
Antiseizure medicine reviewWhen video EEG confirms only dissociative seizures, neurology designs a gradual agent-specific taper using the BNF rather than abrupt cessation.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom