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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Occipital neuralgia

Neurology · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

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Escalate

Occipital neuralgia does not cause systemic illness or focal neurological deficit. A first thunderclap posterior headache, meningism, fever, altered consciousness, papilloedema, acute ataxia, neck trauma with posterior-circulation symptoms or new severe headache in pregnancy, cancer or immunosuppression needs urgent assessment for haemorrhage, infection, arterial dissection, mass lesion or other secondary disease.

Synopsis

Recognise occipital-nerve pain without turning a descriptive tenderness finding into a diagnosis, exclude dangerous posterior headache causes, and coordinate rehabilitation, diagnostic block and specialist intervention proportionately.

  • Occipital neuralgia is recurrent unilateral or bilateral shooting, stabbing or sharp pain in the distribution of the greater, lesser or third occipital nerves, usually lasting seconds to minutes.
  • Pain begins in the upper neck or posterior scalp and can radiate toward the vertex or behind the eye through trigeminocervical convergence; radiation alone does not establish migraine.
  • Scalp dysaesthesia, allodynia and tenderness over the affected nerve are supportive, particularly when pressure reproduces the familiar paroxysm rather than generic muscular discomfort.
  • Diagnostic criteria include temporary improvement after local-anaesthetic block, but a block is not perfectly specific and should be interpreted alongside the complete phenotype.
  • Cervicogenic headache is typically provoked by neck movement with restricted range and referred pain, while migraine more often has hours-long attacks, nausea, sensory sensitivity and activity aggravation.
  • Examine the scalp, cervical spine, neurological system and fundi where indicated; occipital tenderness can accompany migraine, whiplash, myofascial pain and upper-cervical joint disease.
  • Imaging is not automatic in a stable classic presentation, but red flags, abnormal examination, recent trauma, malignancy, infection risk or an atypical progressive pattern justify targeted brain or cervical imaging.
  • Initial care commonly combines explanation, avoidance of repeated pressure, sleep and ergonomic adjustment, physiotherapy and a time-limited neuropathic-pain medicine trial selected for the individual.
  • An ultrasound-guided or landmark occipital-nerve block may support diagnosis and provide temporary relief; consent must cover local-anaesthetic toxicity, bleeding, infection, alopecia or steroid effects where relevant.
  • Persistent disability belongs in headache, pain or neurology services; radiofrequency, peripheral nerve stimulation and decompressive surgery have selected roles but limited evidence and require multidisciplinary selection.

Key red flags

Secondary warning sign

Progression, constitutional symptoms, neurological deficit, papilloedema, cancer, immunosuppression or a major change after trauma should displace the benign working diagnosis.

Investigation priorities

01
Headache chronology and mappingFirst step

Determine whether the pain has a nerve-territory paroxysmal phenotype.

Management branches

First assessmentMap pain and screen for danger

A patient presents with posterior scalp or upper-neck pain.

  1. Establish whether attacks are brief, shooting and nerve-distributed, then ask about thunderclap onset, fever, trauma, cancer, immunosuppression, visual change and focal neurological symptoms.
  2. Examine scalp and nerve emergence points, cervical movement, cranial nerves, limbs and gait, adding fundoscopy and vascular assessment where the differential requires them.
  3. Escalate any secondary-headache feature immediately; otherwise explain the provisional diagnosis and acknowledge overlapping migraine or mechanical pain when present.
Conservative careReduce peripheral and cervical drivers

The phenotype is stable and no urgent secondary cause is suspected.

  1. Identify repeated pressure, sleep position, sustained neck posture and movement restriction, then agree feasible ergonomic adjustments without prescribing rigid immobilisation.
  2. Refer for physiotherapy when cervical dysfunction contributes, using graded mobility, posture and strengthening rather than forceful high-velocity manipulation near vascular structures.
  3. Consider a time-limited neuropathic-pain medicine trial with a pre-agreed functional target, adverse-effect review and stopping plan if benefit is not meaningful.

Key medicines

AmitriptylineFor neuropathic pain, a typical oral start is 10 mg at night with slow titration under the current BNF and local formulary; lower starts may suit frailty.Anticholinergic burden, postural hypotension, sedation, cardiac disease, glaucoma, urinary retention and overdose toxicity limit use; review driving and do not continue without measurable benefit.
GabapentinUse the current BNF neuropathic-pain schedule with low initiation, gradual titration and renal dose adjustment rather than copying a fixed maximum.Dizziness, somnolence, falls, oedema, misuse and respiratory depression with opioids require review; taper rather than stop abruptly after sustained exposure.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • International Headache Society occipital neuralgia criteriaRecognised phenotype, examination findings and block response.
  • NICE CG150 headache recommendationsSecondary-headache warning features, assessment and referral.
  • Faculty of Pain Medicine standards and guidanceUK pain-service standards, interventions and governance resources.
  • BNF neuropathic pain treatment summaryUK medicine selection, titration and adverse-effect framework.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom