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Posterior circulation stroke

Essential points for quick revision.

Synopsis

Recognise vertebrobasilar stroke beyond FAST, localise brainstem, cerebellar and occipital syndromes, and obtain urgent vascular and tissue imaging for reperfusion and swelling management.

  • Posterior circulation stroke can present with diplopia, dysarthria, dysphagia, vertigo, nystagmus, ataxia, visual field loss, crossed sensory findings or reduced consciousness and may be FAST-negative.
  • Basilar artery occlusion can fluctuate or progress to quadriparesis, coma or locked-in syndrome and requires immediate CTA and thrombectomy-centre discussion.
  • Isolated dizziness is usually not stroke, but an acute continuous vestibular syndrome with inability to stand, central eye signs, new headache or focal neurology demands urgent expert assessment.

Key red flags

Reduced consciousness, bilateral weakness, new respiratory irregularity or rapidly evolving cranial-nerve signs suggests basilar occlusion or brainstem compression and needs immediate airway and thrombectomy-centre escalation.

Investigation priorities

01
Non-contrast CT brainFirst step

Exclude intracranial haemorrhage and detect a large established posterior infarct, hydrocephalus or another structural lesion.

Management branches

VERTIGOAcute continuous vestibular syndrome

New continuous vertigo, nausea, nystagmus and gait unsteadiness persist for hours rather than brief positional spells.

  1. Check glucose and observations and examine pupils, ocular alignment and movement, nystagmus, cranial nerves, speech, limbs, coordination and ability to sit or stand safely.
  2. Use HINTS only if trained and the patient meets its intended syndrome; any central sign or unresolved high-risk presentation needs urgent stroke assessment.
AFTERMechanism and recovery

The posterior circulation infarct is stable after acute reperfusion and complication decisions.

Key medicines

AspirinAfter haemorrhage has been excluded, give 300 mg once daily by a swallow-safe route for acute ischaemic stroke, delaying until 24-hour imaging after thrombolysis.
AlteplaseFor an eligible disabling posterior circulation ischaemic stroke, use 0.9 mg/kg intravenously to a maximum 90 mg, with 10% as a bolus and the remainder over 60 minutes.
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Sources and review status5 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom