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RapidMLAMSRAFoundation

Radiculopathy and prolapsed intervertebral disc

Essential points for quick revision.

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Escalate

New saddle or genital sensory change, impaired urinary initiation or flow sensation, loss of rectal fullness, severe progressive bilateral weakness, myelopathic gait or major trauma, cancer or infection features requires emergency spinal assessment. A routine sciatica pathway is unsafe until these are excluded.

Synopsis

Diagnose cervical and lumbar nerve-root syndromes clinically, identify cord and cauda-equina emergencies and use imaging, medicines, activity and surgery according to disability and concordant anatomy.

  • Radiculopathy is a nerve-root syndrome producing dermatomal pain or sensory symptoms, myotomal weakness and a corresponding reflex change; pain without objective deficit may still be radicular.
  • Disc prolapse is one cause among foraminal stenosis, osteophyte, tumour, infection, inflammation and postoperative scar; an MRI disc bulge is common and does not prove symptom causation.
  • Cervical roots cause neck-to-arm pain, paraesthesia and segmental weakness; lumbar roots cause back-to-leg sciatica, with L5 and S1 common but clinically overlapping.

Key red flags

Cauda-equina red flags

Bilateral sciatica or progressive weakness accompanies saddle, genital, urinary flow, bowel fullness or sexual dysfunction and requires emergency MRI rather than routine conservative care.

Investigation priorities

01
Neurological root and cord examinationFirst step

Demonstrate a coherent myotomal, dermatomal and reflex pattern and exclude myelopathy or cauda-equina disease.

Management branches

Initial assessmentLocalise and screen danger

Neck-to-arm or back-to-leg pain suggests a nerve-root syndrome.

  1. Define distribution, onset, cough or movement provocation and functional loss, then test myotomes, reflexes, sensation and tension signs and screen cord, cauda-equina, cancer, infection and trauma features.
  2. Use emergency MRI and specialist routes for red flags; otherwise explain the favourable natural history, encourage normal activity and avoid routine non-specialist imaging.

Key medicines

NSAIDUse the lowest effective formulary dose for the shortest possible period after risk assessment.
Short-course weak opioidConsider only for selected acute low-back pain when an NSAID is contraindicated, not tolerated or ineffective.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom