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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

The complete neurological examination

Neurology · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

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Escalate

Stop the routine sequence and escalate immediately if examination identifies reduced or falling consciousness, a new focal deficit within a stroke window, meningism with sepsis, papilloedema with deteriorating neurology, acute cord or cauda equina features, status epilepticus, or bulbar and respiratory weakness.

Synopsis

Perform and communicate a hypothesis-led but sufficiently complete neurological examination that detects emergencies, establishes a reproducible baseline and supports anatomical localisation.

  • Begin before touch: note alertness, interaction, speech, posture, spontaneous movement, asymmetry, involuntary movements, respiratory effort, walking aids and how the patient transfers.
  • Confirm identity, explain the purpose, seek consent, offer a chaperone where appropriate, expose only what is necessary and adapt positioning, hearing, vision and communication support to the patient.
  • Use a fixed core sequence—mental status, cranial nerves, upper limbs, lower limbs, coordination, gait and relevant special tests—but expand or reorder it when physiology or the presenting problem demands.
  • Compare sides and test from an expected normal area toward abnormal. Recheck surprising findings and distinguish 'not tested', 'unable because of pain' and a genuine neurological deficit.
  • For each limb record inspection, tone, power by named movement, reflexes, plantar responses and sensation by modality; the phrase 'neurology normal' is not a defensible examination record.
  • Power grading requires maximal voluntary effort, good positioning and pain control. Look for drift, fatigability, pyramidal distribution and functional inconsistency rather than relying on a single MRC number.
  • Reflexes are interpreted as a pattern. Reinforcement can reveal a present reflex; clonus and an extensor plantar response add central evidence, while absent reflexes require intact technique and relaxation.
  • Cranial assessment should include fields, pupils and eye movements as well as face, hearing, palate, tongue and speech; visual acuity and fundoscopy are added when symptoms or raised-pressure risk justify them.
  • Never omit gait merely because limb testing on the couch is normal. Observe initiation, base, stride, arm swing, turning and tandem or heel-toe tasks only when safe.
  • Finish by summarising positive and important negative findings, localising them, stating limitations and arranging repeat examination or escalation rather than simply listing every manoeuvre.

Key red flags

Altered higher function

Impaired attention, orientation, language, memory, praxis, visuospatial awareness or behaviour can be diffuse or focal. Establish whether the patient can engage before interpreting complex commands, cortical sensation or apparent limb weakness.

Pyramidal limb syndrome

Pronator drift, weakness following a pyramidal distribution, velocity-dependent increased tone, brisk reflexes, clonus and an extensor plantar response support corticospinal dysfunction, although not every component is present early.

Meningeal irritation pattern

Headache, photophobia, fever and neck stiffness raise meningitis or subarachnoid haemorrhage concern. Absence of classic meningism, especially in older, immunocompromised or obtunded patients, does not safely exclude either emergency.

Bulbar or ventilatory weakness

Wet or nasal voice, weak palatal movement, poor cough, pooling secretions, fatigable counting, neck flexion weakness or paradoxical breathing can precede gas-exchange abnormalities and needs urgent respiratory assessment.

Investigation priorities

01
Structured conscious-level and cognitive screeningFirst step

Quantify arousal, attention and focal higher-function abnormalities before interpreting the remainder of the examination.

Management branches

Acute focal presentationExamine without delaying reperfusion decisions

New face, arm, leg, speech, visual, neglect, gaze, balance or brainstem dysfunction of sudden or uncertain onset.

  1. Perform ABCDE and glucose, document last known well and rapidly test conscious level, language, gaze, fields, face, all limbs, sensation, coordination and neglect using a stroke-pathway framework.
  2. Activate local stroke imaging and specialist review immediately; do not extend the bedside examination with low-yield manoeuvres when this would delay CT, angiography or transfer.
  3. Time-stamp and repeat the core deficit after imaging, treatment or deterioration, including swallow safety and any posterior-circulation features that a brief screen may miss.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • NICE NG127 adult neurological recognitionNational referral thresholds and examination implications across common neurological presentations.
  • NICE NG232 head injury recommendationsCurrent standards for conscious-level assessment, neurological observation and escalation after head injury.
  • National Clinical Guideline for Stroke assessmentMultidisciplinary UK and Ireland guidance for acute neurological assessment and serial stroke care.
  • NICE CG103 delirium guidanceAssessment and monitoring principles when cognition and cooperation fluctuate.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom