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Educational draft · awaiting clinical reviewThe full textbook explains uncertainty but does not replace live national or local guidance, specialist advice, or current prescribing information.
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Cervical myelopathy

Recognise cervical spinal-cord dysfunction early, distinguish it from nerve-root and peripheral disorders, and match adult degenerative disease severity to safe specialist management.

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Rapidly progressive cervical cord syndrome

New inability to walk, rapidly worsening weakness, bladder dysfunction, a sensory level or respiratory compromise may reflect severe cervical compression rather than routine neck pain.

Action: Immobilise if trauma or instability is possible, document the neurological level, arrange urgent whole-problem MRI and spinal surgical discussion, and investigate tumour, infection, haemorrhage or acute disc disease in parallel.

Open the sections you need. The overview is shown first.
01Core principlesThe concepts and mechanisms needed to understand the subject.

Degenerative cervical myelopathy results from age-related disc, osteophyte, facet, ligamentum flavum or posterior longitudinal ligament change narrowing the canal. Static compression and repeated dynamic injury impair cord perfusion and axons. Symptoms can be subtle, asymmetric and slowly progressive, so the functional history often precedes striking weakness.

Cervical radiculopathy causes dermatomal pain, sensory loss, myotomal weakness and reduced segmental reflexes. Myelopathy adds long-tract dysfunction below the lesion: spasticity, hyperreflexia, gait change and bladder disturbance. Motor neurone disease, multiple sclerosis, vitamin B12 deficiency, peripheral neuropathy and tandem lumbar stenosis may mimic or coexist.

Key points

  • Cervical myelopathy is spinal-cord dysfunction: hand dexterity loss, gait imbalance and upper-motor-neuron leg signs distinguish it from a single cervical root lesion.
  • Examine both arms and legs. A patient describing hand numbness may still have brisk knees, clonus, extensor plantar responses, proprioceptive loss and a broad-based or spastic gait.
  • The worked case keeps context, reasoning, outcome and verification visible in Rapid mode, including the urgent MRI and referral decision.
  • MRI must be clinically correlated because degenerative compression is common in asymptomatic adults; cord dysfunction, level and progression determine significance.
  • AO Spine/CSRS recommends surgery for moderate or severe adult degenerative cervical myelopathy; the purpose is to arrest deterioration and permit recovery, not guarantee normal neurology.
  • For mild DCM, offer surgery or a supervised structured rehabilitation trial; operate if neurological deterioration occurs and consider surgery if improvement does not.
  • Do not transplant chronic DCM guidance to acute trauma, cancer, infection, epidural haematoma or childhood disease; these require their own emergency pathways.
02Mechanisms and patternsImportant relationships and how to distinguish them.
Hand dysfunctionRed flag

Progressive loss of buttoning, handwriting or object grip together with gait change and upper-motor-neuron signs means suspected cervical myelopathy: arrange urgent spinal assessment and cervical MRI.

Gait and long tractsRed flag

Unsteadiness, stiffness, falls, reduced tandem gait, brisk reflexes, clonus and extensor plantar responses support cervical cord dysfunction.

Root-predominant syndrome

Unilateral dermatomal arm pain with myotomal weakness and depressed corresponding reflexes suggests radiculopathy, but concurrent leg signs mean myelopathy.

Posterior column pattern

Impaired joint position, vibration and balance in low light can occur when dorsal cervical cord pathways are compressed.

Non-degenerative clues

Abrupt onset, fever, cancer, trauma, anticoagulation or severe nocturnal pain should redirect immediately toward infarction, infection, tumour, fracture or haematoma.

Red flags requiring action

  • Progressive hand weakness or clumsiness combined with gait deterioration or falls is a cord syndrome until assessed, even without neck pain.
  • New bladder or bowel dysfunction, saddle change, profound limb weakness or a defined sensory level requires emergency assessment rather than routine DCM follow-up.
  • Fever, immunosuppression, cancer history, severe night pain, recent procedure, trauma or anticoagulation changes the aetiology and urgency of cord compression.
  • Respiratory weakness, high cervical sensory change or rapidly ascending deficit requires immediate airway and critical-care planning.
03Interpreting evidenceInformation, measurements and their limitations.
Reasoning sequence

Consider the information, its meaning and its limitations before deciding what follows.

  1. 01
    Complete neurological examination
    Why
    Localise cord, root and peripheral components and establish a reproducible functional baseline.
    Interpretation and limitations
    Bilateral long-tract leg signs plus hand dysfunction support cervical myelopathy; a sensory level or rapid progression increases urgency.
  2. 02
    MRI cervical spine
    Why
    Define cord compression, involved levels, intramedullary signal, alignment and the responsible disc, bone or ligament anatomy.
    Interpretation and limitations
    Compression concordant with the clinical syndrome supports DCM. Incidental stenosis without myelopathic findings is not the same disease state.
  3. 03
    Whole-spine or contrast-enhanced MRI
    Why
    Evaluate an atypical level, suspected tandem stenosis, tumour, infection, inflammatory lesion or epidural collection.
    Interpretation and limitations
    Enhancement, destructive bone change or a non-degenerative lesion moves the patient into an aetiology-specific emergency pathway.
  4. 04
    CT cervical spine
    Why
    Show ossification, osteophytes, fracture, alignment and bony anatomy when MRI is limited or surgery is planned.
    Interpretation and limitations
    CT complements MRI for bone but does not show cord injury as well and should not replace urgent MRI without a specific contraindication.
  5. 05
    Targeted mimic screen
    Why
    Investigate B12 deficiency, inflammatory disease, neuropathy or motor neurone disease when the clinical and imaging pattern is discordant.
    Interpretation and limitations
    A positive mimic may coexist with radiological stenosis; attribution requires concordant examination, not a binary scan label.
04Applied reasoningWorked examples connecting principles to decisions.
01Worked caseProgressive hand and gait dysfunctionAn older adult develops months of buttoning difficulty, falls and brisk leg reflexes with no acute trauma.
  1. 1Context: document pace, hand tasks, walking distance, falls, sphincter symptoms, arm radicular pain and examination of cranial nerves, all limbs, reflexes, plantars, proprioception and gait.
  2. 2Reasoning: recognise the combined hand, gait and long-tract pattern as cervical myelopathy rather than isolated root or median-nerve disease; request cervical MRI and urgent specialist assessment.
  3. 3Outcome: if MRI confirms moderate or severe DCM, discuss decompression; choose anterior or posterior access and stabilisation from level count, compression location, alignment, instability and surgical risk.
  4. 4Verification: record baseline function and severity, then follow strength, dexterity, gait, sphincters, pain and complications; stability can be success because established cord injury may not fully reverse.
02Severity-directedMild versus moderate or severe DCMAdult degenerative compression is clinically and radiologically concordant and alternative emergencies are excluded.
  1. 1Recommend surgery for moderate or severe DCM after shared decision-making about arresting progression, recovery uncertainty and approach-specific harm.
  2. 2For mild DCM, offer surgery or a supervised structured rehabilitation trial with close neurological observation rather than unmonitored reassurance.
  3. 3Operate if deterioration occurs during conservative care and consider surgery when meaningful functional improvement does not occur.
03Atypical emergencyNon-degenerative cervical compressionDeficit is acute, rapidly progressive or accompanied by trauma, malignancy, infection or bleeding risk.
  1. 1Protect alignment when instability is possible and escalate immediately to the spinal team while stabilising respiratory and circulatory physiology.
  2. 2Obtain urgent imaging of the relevant spine, adding contrast or CT according to suspected tumour, infection, haematoma or fracture.
  3. 3Use the matched cause pathway for antimicrobial therapy, haemostasis reversal, steroids, tumour treatment or trauma decompression; chronic DCM rules do not substitute.
05Checking understandingVerify the reasoning, revisit uncertainties and apply feedback.
  • Record dexterity, limb power, reflexes, sensation, gait, falls and sphincter function at each active review so deterioration is detectable rather than described as generic pain.
  • During supervised non-operative care for mild DCM, provide a direct return route for new weakness, walking decline, falls or bladder symptoms and shorten follow-up if change occurs.
  • After decompression, monitor wound, swallowing or voice after anterior surgery, C5 weakness, haematoma, infection, neurological change and construct integrity according to approach.
  • Assess patient-defined activities such as writing, work, stairs and walking aids alongside formal scores because neurological stabilisation may still yield functional goals.
  • Continue rehabilitation and falls prevention without high-risk neck manipulation; persistent neuropathic symptoms do not automatically prove recurrent compression.
06Special situationsVariants, exceptions and circumstances that change the usual approach.

Pain may be absent

Degenerative cord compression can present through hands and gait with little neck or radicular pain, which contributes to diagnostic delay.

Hoffmann is not enough

One reflex sign lacks diagnostic specificity; combine it with history, long-tract findings, gait and concordant imaging.

Imaging is common

Age-related canal narrowing may be incidental, so treatment requires clinical myelopathy rather than a radiology phrase alone.

Surgery changes trajectory

The realistic aim is prevention of further cord injury with possible recovery; chronic severe deficits may remain despite adequate decompression.

Root and cord coexist

Foraminal stenosis can cause arm pain and reduced segmental reflexes while central compression simultaneously produces brisk legs and gait change.

07Common pitfallsFrequent interpretation and management errors.
  1. 01

    Calling bilateral hand symptoms carpal tunnel syndrome without examining gait, reflexes and plantar responses.

  2. 02

    Using absence of neck pain or a single normal reflex to exclude cervical myelopathy.

  3. 03

    Treating moderate or progressive DCM with indefinite unsupervised physiotherapy while neurological function declines.

  4. 04

    Promising neurological normality after decompression instead of explaining arrest, recovery uncertainty and complication risk.

  5. 05

    Applying adult degenerative guidance to traumatic, malignant, infective or paediatric cervical cord compression.

Practice

Two practice questions

Question 1 of 20 correct
NeurosurgeryOriginal SBA

Recognising cervical cord disease

A 67-year-old has progressive hand clumsiness, difficulty fastening buttons, an unsteady gait, brisk leg reflexes and extensor plantar responses. What is the most appropriate interpretation?

Sources and review status3 sources · checked 13 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 13 Sept 2026; clinical approval remains outstanding.

  • NICE NG127 suspected neurological conditionsNICE NG127, first published 1 May 2019 and last reviewed 2 October 2023; adult cervical/lumbar radiculopathy referral recommendation 1.10.11 read 13 September 2026. Gait disturbance, clumsy or weak hands or legs, brisk reflexes and extensor plantar responses are myelopathic exceptions to routine stable-radiculopathy care. Chapter-specific use: cervical myelopathy.
  • AO Spine CSRS degenerative cervical myelopathy guidelineFehlings et al., Global Spine Journal 2017; recommendations for mild, moderate and severe DCM and non-myelopathic cord compression read 13 September 2026. Surgery is recommended for moderate/severe disease; mild DCM may have surgery or a supervised structured rehabilitation trial with surgery if deterioration or failure to improve. Chapter-specific use: cervical myelopathy.
  • AO Spine degenerative cervical myelopathy recommendations updateAO Spine clinical practice recommendations, Global Spine Journal 2025; diagnosis, MRI prognostic evidence and management of mild DCM read 13 September 2026. Adult DCM update supports timely specialist decision-making but does not create a UK referral standard or a universal surgical approach. Chapter-specific use: cervical myelopathy.
Authoring stateComplete draftClinical stateAwaiting reviewJurisdictionUnited Kingdom