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Fibroids, polyps and adenomyosis

Essential points for quick revision.

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Escalate haemorrhage, torsion-like pain or sepsis

Shock from uterine bleeding, severe acute pain with a mass, fever after instrumentation, urinary obstruction or rapidly enlarging postmenopausal mass requires urgent gynaecological assessment rather than routine fibroid or adenomyosis follow-up.

Action: Stabilise, exclude pregnancy, obtain urgent bloods and imaging appropriate to physiology, involve senior gynaecology and pursue haemostasis, infection control or surgery according to the acute mechanism.

Synopsis

Distinguish fibroids, endometrial polyps and adenomyosis by compartment and symptom pattern, select ultrasound or hysteroscopy, and match medical, hysteroscopic, radiological or surgical treatment to anatomy and fertility priorities.

  • Fibroids are benign myometrial smooth-muscle tumours; submucosal lesions distort the cavity and commonly drive bleeding, intramural lesions enlarge the wall and subserosal lesions more often cause pressure.
  • Endometrial polyps are focal cavity overgrowths that commonly cause intermenstrual, postcoital or irregular bleeding and require histology when removed.
  • Adenomyosis is endometrial-type tissue within myometrium, typically producing heavy painful periods, chronic pelvic pain and a diffusely bulky tender uterus.

Key red flags

Postmenopausal bleeding or a newly enlarging postmenopausal uterine or endometrial lesion requires urgent malignancy assessment rather than presumptive benign disease.

Atypical postmenopausal mass

New growth, bleeding, pain or suspicious imaging after menopause requires urgent specialist assessment because a presumed fibroid diagnosis is not sufficient.

Investigation priorities

01
Pregnancy test and full blood countFirst step

Exclude pregnancy-related bleeding and measure anaemia while structural assessment proceeds.

Management branches

Cavity lesionInspect and treat polyps or submucosal fibroids

Intermenstrual bleeding, imaging or HMB suggests a focal endometrial-cavity lesion.

  1. Offer outpatient hysteroscopy, explain analgesia and anaesthetic alternatives and obtain consent for biopsy or see-and-treat removal if appropriate.
  2. Remove a symptomatic polyp or suitable submucosal fibroid hysteroscopically and send all tissue for histological examination.
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Sources and review status5 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom