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Intraocular pressure measurement

Measure and document intraocular pressure safely, recognise method-related uncertainty and interpret the result alongside symptoms, optic-nerve structure, fields and anterior chamber anatomy.

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Pressure-related emergency or an unsafe globe

A painful red eye with blurred vision, haloes, headache or vomiting may represent acute angle closure; trauma may make pressure measurement itself unsafe.

Action: Arrange immediate ophthalmic assessment for suspected acute angle closure. If an open globe is possible, do not perform tonometry or press the eye; protect it with a non-compressive rigid shield and obtain emergency help.

Open the sections you need. The overview is shown first.
01Purpose and principlesWhat the assessment is for and the core concepts behind it.

Intraocular pressure reflects the balance between aqueous humour production and outflow, principally through the drainage angle. Tonometry estimates that pressure from the eye's response to a mechanical interaction; it does not directly measure optic-nerve health. A raised value may occur without established glaucomatous damage, while glaucoma can develop at values that are not above a population reference range. This distinction matters whenever an apparently reassuring number is used to dismiss suspicious field loss or a damaged-looking nerve.

Goldmann applanation tonometry measures the force needed to flatten a defined area of the cornea. At the slit lamp, fluorescein and topical anaesthetic allow a prism to contact the central cornea while the examiner identifies a standard optical endpoint. NICE specifies Goldmann-type applanation for glaucoma case finding and slit-lamp-mounted Goldmann applanation as part of diagnostic assessment. A handheld applanation device can be useful when positioning is difficult, but the method and conditions still need recording. A numerical result from one instrument should not automatically be treated as interchangeable with every other instrument.

Non-contact tonometry uses an air pulse, while rebound tonometers use the behaviour of a small probe briefly contacting the cornea. Rebound measurement often needs no anaesthetic and can support selected clinical or home monitoring arrangements after training. These approaches have practical advantages, but readings can differ with corneal properties and technique. A screening air-puff result should lead to an appropriate clinical assessment rather than a stand-alone glaucoma diagnosis or referral decision. Device quality indicators help identify unreliable readings, but a favourable indicator cannot remove all clinical sources of error.

Decide whether measurement is safe before preparing the drops. Ask about trauma, corneal disease, recent surgery, medicines and previous glaucoma treatment. Inspect the eye for signs that contact or pressure might be harmful. Suspected open-globe injury is a contraindication to tonometry, including an air-puff attempt; protect the eye and seek urgent specialist care instead. An ulcerated or markedly abnormal cornea and some postoperative circumstances need expert advice about the safest method and the interpretability of any result. Do not palpate an injured eye as a substitute for an unavailable instrument.

For Goldmann measurement, explain the brief contact and position the patient comfortably at the slit lamp with stable forehead and chin support. Check the instrument's calibration status and use a compatible clean prism or appropriate single-use tip. Administer the selected anaesthetic and fluorescein correctly. Ask the patient to breathe normally, look ahead and avoid squeezing the lids. Advance the prism gently to the central cornea under observation, obtain the two fluorescent semicircles and adjust to the endpoint where their inner borders meet. Withdraw before reading and documenting the final result according to the device's scale and instructions.

Reliable technique includes noticing when the image is unsuitable. Poor alignment, an irregular tear film, excess fluorescein, corneal scarring or lid squeezing can affect the result. Supporting a lid must not put force through the globe. If a reading is implausible or discordant with the examination, correct an identifiable technical problem and repeat within an appropriate plan. Do not repeatedly applanate a painful or damaged surface just to obtain a preferred number. Significant astigmatism and abnormal corneal anatomy may need specific technique or an alternative device chosen by an experienced examiner.

Corneal thickness and biomechanics influence applanation, so pressure belongs alongside central corneal thickness and the rest of a glaucoma assessment. A thick or thin cornea should prompt thoughtful interpretation rather than an invented universal correction formula. Prior corneal refractive surgery can further complicate comparison with previous readings. Pressure also varies over time and can be affected by treatment timing and adherence. Record these circumstances when following an established patient; a change between visits may reflect disease, treatment, measurement conditions or a combination.

For an adult without acute symptoms undergoing glaucoma case finding, NICE recommends considering a repeat pressure or field assessment before referral when appropriate. Refer for optic-nerve damage, a consistent glaucomatous field defect or pressure of at least 24 mmHg on Goldmann-type applanation, with results accompanying the referral. The threshold is a case-finding criterion, not an acute angle-closure definition and not a guarantee that 23 mmHg is harmless. Urgent clinical circumstances bypass repetition on another occasion. The College of Optometrists lists pressure of 40 mmHg or more as requiring emergency assessment within twenty-four hours independently of cause; symptoms may require attention sooner.

Measurement ends with communication and follow-up. Explain whether the value is reassuring in context, needs confirmation or requires specialist assessment, and distinguish suspicion from an established diagnosis. In glaucoma monitoring, the treating service sets a target and review interval from disease severity, progression and treatment tolerance. Patients using prescribed drops should continue their existing plan unless an appropriate clinician changes it. A single lower reading should not prompt unsupervised treatment cessation, and a higher reading needs assessment of symptoms, adherence, technique and the intended target rather than automatic self-escalation.

Key points

  • Intraocular pressure is a risk factor and treatment target, but one pressure value does not diagnose or exclude glaucoma.
  • Use Goldmann-type applanation measurements in the NICE glaucoma referral assessment; do not refer solely on an air-puff result.
  • Before measurement, consider trauma, corneal ulceration, recent surgery, device suitability and the safety of corneal contact.
  • Document the eye, pressure in mmHg, instrument, time, measurement quality and relevant treatment or corneal factors.
  • For non-urgent glaucoma case finding, NICE uses 24 mmHg or more on Goldmann-type applanation as one referral criterion after considering repeat measurement.
  • Optic-nerve damage or a glaucomatous field defect can justify referral even when pressure is below 24 mmHg.
  • Acute symptoms or markedly raised pressure override routine repeat-measurement pathways; discuss urgency with the eye service.
02Indications, selection and cautionsWhen it is useful, when urgency changes and important limitations.
Acute angle-closure pattern

Pain, blurred vision, haloes, headache, nausea or vomiting with a red eye and possible corneal clouding suggests an emergency. A missing or technically poor pressure value must not postpone urgent ophthalmic assessment.

Elevated value without acute symptoms

An asymptomatic raised reading needs confirmation and interpretation with the method, optic nerve, visual field and angle assessment. Check whether the case belongs to routine referral refinement or a more urgent pressure pathway.

Suspicious nerve or field at a lower pressure

A pressure below the referral threshold does not cancel structural damage or a compatible field defect. These findings can independently warrant glaucoma assessment and should be included in the referral.

Discordant or unreliable result

A large unexpected change, poor-quality mires, squeezing or a markedly abnormal cornea may make a reading misleading. Address the technical issue and obtain appropriate reassessment without ignoring accompanying dangerous symptoms.

Red flags requiring action

  • Severe ocular pain with nausea, vomiting, reduced vision or a cloudy cornea requires emergency assessment even when a reliable pressure reading is unavailable.
  • After an injury, a peaked pupil, visible wound or high-risk mechanism requires exclusion of an open globe before any tonometry is considered.
03Method and interpretationA systematic approach to the test and its findings.
Investigation order

Read from the initial assessment onwards. Tests may run in parallel in urgent care; first-line, preferred, confirmatory, definitive and gold-standard labels appear only when the chapter explicitly states them.

  1. 01
    Goldmann-type applanation for case findingFirst step
    Why
    Provide the pressure measurement used in the NICE referral assessment.
    Interpretation and limitations
    Interpret an IOP of 24 mmHg or more alongside the other findings and consider repeat measures if circumstances are non-urgent. Do not postpone emergency care merely to meet a routine confirmation process.
  2. 02
    Optic-nerve and visual-field assessment
    Why
    Identify structural and functional damage beyond the pressure measurement.
    Interpretation and limitations
    Stereoscopic nerve assessment and appropriate automated perimetry are complementary. A compatible abnormality may require referral despite pressure below 24 mmHg, and unreliable fields need interpretation rather than automatic dismissal.
  3. 03
    Anterior chamber angle assessment
    Why
    Assess the drainage configuration and identify an angle-closure risk.
    Interpretation and limitations
    Gonioscopy is part of diagnostic glaucoma assessment. Other depth assessments can be used in specified circumstances, but an IOP reading alone cannot determine whether the angle is open.
  4. 04
    Central corneal thickness and measurement context
    Why
    Identify factors affecting pressure interpretation and longitudinal comparison.
    Interpretation and limitations
    Corneal thickness, surgery, irregularity and measurement technique can influence the result. Record these factors and avoid applying an unsupported correction rule to manufacture a supposedly exact true pressure.
04Clinical next stepsHow the result changes management or prompts escalation.
01PreparationConfirm safety and instrument readinessFirst stepPressure measurement is indicated and the clinical setting permits assessment.
  1. 1Review ocular injury, surgery and surface disease, inspect for contraindications and choose a suitable measurement method.
  2. 2Confirm the instrument and tip are appropriate, calibrated and prepared under current infection-control and manufacturer instructions.
  3. 3Explain the procedure and position the patient without external pressure on the globe, documenting anything likely to compromise the result.
02MeasurementObtain a defensible pressure readingGoldmann applanation is appropriate and a trained examiner is available.
  1. 1Use the selected diagnostic drops correctly and obtain a centred fluorescent image with the patient relaxed and looking forward.
  2. 2Identify the proper mire endpoint, withdraw the prism safely and record the pressure with laterality, time and method.
  3. 3AlternativeCorrect a clear technical problem and repeat if necessary, or seek an alternative expert assessment when the cornea or circumstances prevent reliable measurement.
03Clinical actionChoose follow-up from the whole examinationA pressure value must be interpreted for referral or ongoing glaucoma care.
  1. 1Assess pain, vision, corneal appearance and other urgent findings before using a non-urgent referral threshold.
  2. 2Combine pressure with nerve, field and angle findings, considering repeat measurement only when delay is clinically appropriate.
  3. 3Send the measurements and relevant history with the referral, explain the urgency and ensure continued treatment and safety-net advice while awaiting review.
05Procedure and medicine safetyRelevant preparation, treatment and contraindications.
Short topical anaesthesia to permit appropriate corneal contact during pressure measurement.

Minims proxymetacaine hydrochloride 0.5% eye drops

For tonometry, instil one or two drops topically into the eye immediately before measurement, then stop after the procedure and discard the single-use unit. Allow at least one minute before administering another topical agent such as fluorescein.

Do not use with hypersensitivity; avoid this ester local anaesthetic in premature babies because its metabolism is immature. Use sparingly with allergy history, cardiac disease, hyperthyroidism or ocular inflammation, and in pregnancy or lactation only if essential. Repeated prolonged use damages corneal epithelium; avoid rubbing while numb and driving while vision is blurred. Do not mix this product directly with fluorescein in a container.

06Risks, monitoring and follow-upComplications, safety checks and further assessment.
  • In serial glaucoma care, record the current drops, recent administration and adherence difficulties alongside the measured pressure.
  • Compare readings using their instrument and circumstances, and consider whether corneal surgery or a new surface problem has changed interpretability.
  • Ensure patients understand the distinction between a repeat-measurement appointment, a diagnostic referral and established glaucoma follow-up.
  • Advise urgent help for new severe pain, red eye, haloes, vomiting or deteriorating vision regardless of a previously acceptable reading.
07Special situationsVariants, exceptions and circumstances that change the usual approach.

Pressure thresholds serve particular decisions

A referral threshold, a population reference range and an individual's treatment target answer different questions. Keep those purposes separate when explaining a number to a patient.

Infection control is part of accuracy and safety

A damaged prism or residual disinfectant can injure the cornea as well as compromise examination. Follow the device-specific decontamination and inspection process, including required rinsing before contact.

A quiet eye can still require prompt care

Markedly elevated pressure is not always accompanied by dramatic pain. Arrange appropriate urgency from the value, cause and associated findings rather than making pain a mandatory criterion.

Home readings require a clinical framework

Selected patients may record pressure outside clinic using an agreed device and training. The reviewing service should define how to interpret results and when to seek help rather than encouraging unsupervised treatment changes.

08Common pitfallsFrequent interpretation and management errors.
  1. 01

    Equating a single high pressure with glaucoma or a lower pressure with absence of glaucomatous disease.

  2. 02

    Using a non-contact screening reading as the sole reason for a glaucoma referral without the assessment specified by NICE.

  3. 03

    Applying pressure to the lid or performing tonometry when an open-globe injury is possible.

  4. 04

    Subtracting an arbitrary number for corneal thickness or mixing readings from different instruments without considering their limitations.

Practice

Two practice questions

Question 1 of 20 correct
OphthalmologyOriginal SBA

Assessing an isolated screening pressure

An asymptomatic adult has an air-puff pressure of 27 mmHg during a screening visit. No optic-nerve or visual-field assessment has yet been performed. Which next step best follows NICE glaucoma case-finding guidance?

Sources and review status7 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateComplete draftClinical stateAwaiting reviewJurisdictionUnited Kingdom