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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
RapidMLAMSRAGP

Primary open-angle glaucoma and ocular hypertension

Essential points for quick revision.

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Sudden symptoms require another pathway

Chronic open-angle glaucoma is usually painless; a suddenly painful red eye with blurred vision and vomiting may have acute angle closure or another ocular emergency.

Action: Arrange immediate emergency eye assessment for acute pain or visual deterioration instead of waiting for routine glaucoma referral or repeat pressure measurements.

Synopsis

Distinguish glaucomatous optic neuropathy from isolated pressure elevation, assess lifetime visual risk, and select an appropriate diagnostic and initial treatment pathway.

  • Glaucoma is progressive optic nerve damage with corresponding structural or functional loss; ocular hypertension describes raised pressure without established glaucomatous damage.
  • A pressure within the usual population range does not exclude glaucoma, and an isolated high reading does not establish optic neuropathy.
  • Assess the optic discs, visual fields, angle and Goldmann applanation pressure; measure central corneal thickness during diagnostic assessment.

Key red flags

New severe ocular pain, corneal haze, nausea or abrupt visual loss is inconsistent with uncomplicated chronic disease and requires urgent same-day ophthalmic assessment.

Investigation priorities

01
Goldmann applanation and repeat measuresFirst step

Establish pressure with an appropriate method and assess reproducibility.

Management branches

Case findingConfirm the referral indication

A routine eye assessment identifies raised pressure or possible glaucomatous damage.

  1. Assess the disc, fields and angle and obtain Goldmann-type pressure measurements before deciding the routine referral pathway.
  2. Repeat uncertain measurements when clinically appropriate, while bypassing repeat-measure pathways if symptoms or severity require urgent assessment.

Key medicines

Latanoprost 50 micrograms/mL eye dropsInstil one drop into each affected eye once daily, preferably in the evening; continue long term until the glaucoma team changes or stops treatment.
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Sources and review status4 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom