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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Acute pain and procedural distress

Paediatrics and child health · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
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Severe pain with physiological instability or sedation complication

Pain with shock, compartment syndrome, meningism, acute abdomen, testicular torsion, ischaemia or reduced consciousness is a signal to treat pain while diagnosing a time-critical cause. Airway obstruction, apnoea, hypoxaemia or hypotension during sedation is a resuscitation emergency.

Action: Use ABCDE, call senior and specialty help, give prompt titrated analgesia and treat the cause. If sedation causes respiratory compromise, stop the procedure, stimulate, open the airway, give oxygen and bag-mask ventilation, call for resuscitation support and use a specific reversal agent only when indicated and supported by ongoing observation.

Synopsis

Assess pain developmentally, provide prompt multimodal analgesia, distinguish analgesia from sedation, prepare children psychologically and deliver procedures with consent, monitoring, rescue capability and equitable reassessment.

  • Pain is what the child experiences; use self-report whenever development allows and behavioural tools when it does not.
  • First-line assessment combines site, quality, severity, timing, function and red flags with an age-appropriate validated scale.
  • Give analgesia during assessment; it does not prevent diagnosis and severe pain should receive an appropriate medicine within about 20 minutes.
  • Use multimodal care: comfort and positioning, explanation, distraction, topical or local anaesthesia and weight-based systemic analgesia.
  • Paracetamol is useful for mild pain; add ibuprofen when inflammation is relevant and there is no dehydration, renal, bleeding, asthma or other contraindication.
  • For severe pain without IV access, intranasal fentanyl is a rapid first-line option in an appropriately monitored emergency setting for eligible children.
  • Reassess pain, sedation, physiology and function after every intervention and before repeating or escalating medication.
  • Procedural analgesia and sedation are different: local anaesthetic treats pain, while sedation reduces distress or movement but may not provide analgesia.
  • NICE first-line options for painless procedures include distraction plus nitrous oxide or oral or intranasal midazolam when suitable; painful procedures also require local anaesthesia.
  • Ketamine or IV midazolam with or without fentanyl requires trained sedation staff, an independent assistant, monitoring and airway rescue capability.
  • Seek consent from the person with parental responsibility and the capable young person; seek the child's assent and respect communication and sensory needs.
  • Discharge only after return to baseline consciousness, stable observations, adequate pain control, safe mobility and clear medicine and return advice.

Key red flags

Pain out of proportion, pain on passive stretch, tense swelling, pallor, coolness or neurological change suggests compartment syndrome or ischaemia.

Bilious vomiting, guarding, rigid abdomen, sudden scrotal pain, meningism, focal neurology or a non-blanching rash requires urgent diagnostic escalation despite analgesia.

Unexpected bruising, repeated injuries, inconsistent history, pain behaviour around a caregiver or genital injury requires safeguarding assessment.

Reduced consciousness, obstructive sleep apnoea, difficult airway, cardiorespiratory disease, fasting aspiration risk or previous sedation reaction increases procedural-sedation risk.

No response to apparently adequate analgesia demands reassessment of diagnosis, dose, route, delivery and evolving complications rather than repeated unstructured dosing.

Apnoea, stridor, loss of verbal contact, oxygen desaturation, hypotension or paradoxical agitation during sedation requires immediate rescue.

Investigation priorities

01
First-line validated pain scoreFirst stepFirst line

Establish severity and provide a reproducible response measure.

Management branches

Initial pain careAssess, treat, reassess

A child presents with acute pain.

  1. Use ABCDE and identify any time-critical underlying causes.
  2. Record an age-appropriate pain and functional score.
  3. Give non-drug support and weight-based multimodal analgesia promptly.
  4. Repeat the same score and physiology at expected onset and escalate if inadequate.

Key medicines

ParacetamolA commonly used acute paediatric oral dose is 15 mg/kg per dose, subject to age-specific product limits, dosing interval and local maximum daily dose; check previous and combination-product exposure.Use local or BNF for Children dosing for age, weight and route; reduce or seek advice in low body weight, malnutrition, hepatic impairment or repeated dosing and treat overdose through NPIS guidance.
IbuprofenUse the age- and weight-specific oral dose in the current BNF for Children or local formulary, usually divided up to three or four times daily for the shortest necessary course.Avoid or seek advice with significant dehydration, kidney injury, active bleeding or ulceration, relevant NSAID hypersensitivity, severe asthma sensitivity and varicella; do not combine multiple NSAIDs.
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Sources and review status4 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • NICE CG112 sedation in under 19sCurrent UK assessment, consent, fasting, medicine-selection, monitoring, staffing and recovery recommendations.
  • NHSGGC paediatric emergency pain managementCurrent reviewed UK pathway for timely analgesia, pain scales, intranasal fentanyl and monitoring.
  • NHSGGC paediatric acute pain service protocolUpdated multidisciplinary acute-pain principles and opioid safety.
  • NHSGGC sedation for diagnostic and therapeutic proceduresUK service framework for risk assessment, monitoring and recovery.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem ·

Content changes
Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom