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Newborn life-support principles

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Apnoea, gasping or profound neonatal bradycardia

A newborn who is not breathing effectively or has a heart rate below 100/min needs immediate airway opening and positive-pressure ventilation; a rate below 60/min despite effective ventilation triggers compressions.

Action: Call trained help, start the clock, maintain temperature and assess breathing, heart rate and tone. Place the head neutral, apply jaw thrust and begin 5 inflation breaths promptly when breathing is absent or ineffective or heart rate is below 100/min. Confirm visible chest movement and a rising heart rate before advancing. If the chest does not move, correct mask seal and airway position, repeat inflations, use a two-person technique or alternative airway and increase pressure incrementally. After lung inflation give ventilation breaths at 30/min. Begin 3:1 coordinated chest compressions only when heart rate remains below 60/min after at least 30 seconds of effective ventilation.

Synopsis

Prepare safely for birth, support normal transition, prioritise effective lung inflation when a newborn is compromised, escalate through ventilation, compressions and drugs in the 2025 UK sequence, and provide temperature, glucose, family and post-resuscitation care.

  • Before birth brief the team, allocate roles, check warmer, gas supply, blender, suction, ventilation interfaces, oximeter, ECG, airway equipment, emergency access and drugs.
  • Aim for cord clamping after at least 60 seconds while warming, stimulating and assessing when safe; never delay necessary resuscitation that cannot be delivered with the cord intact.
  • Maintain 36.5–37.5°C. At less than 32 weeks, place the body in a polyethylene wrap without drying, dry and cover the head and use a preheated radiant warmer.

Key red flags

Absent or ineffective breathing, gasping, marked hypotonia or heart rate below 100/min requires immediate respiratory support rather than prolonged stimulation.

Investigation priorities

01
First-line monitoring: heart rate and breathingFirst stepFirst line

Determine whether transition is adequate and measure the response to every ventilation or compression cycle.

Management branches

PreparationBrief, warm and check

Birth is imminent or neonatal compromise is anticipated.

  1. Review gestation, fetal condition, maternal history and agreed extent of care and summon an appropriately skilled team.
  2. Allocate leadership, airway, monitoring, access, documentation and family support and check every item before birth.

Key medicines

Adrenaline 1:10,000, 0.1 mg/mLIf heart rate remains below 60/min after effective ventilation and 30 seconds of compressions, give 20 micrograms/kg, equivalent to 0.2 mL/kg, by umbilical venous or intraosseous route; repeat every 4 minutes while indicated. If intubated without vascular access, give 100 micrograms/kg, 1 mL/kg, intratracheally as a bridge.
Glucose 10%Check blood glucose during prolonged resuscitation where possible. If it is low, give 200 mg/kg, equivalent to 2 mL/kg of 10% glucose, intravenously or intraosseously, then provide gestation-appropriate infusion and repeat measurement under the neonatal protocol.
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Sources and review status3 sources · checked 27 Aug 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom