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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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Aseptic technique and peripheral intravenous cannulation

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Synopsis

Create and maintain an aseptic field and insert, secure, access, assess and remove a peripheral IV cannula safely within local competence and infection-prevention standards.

  • Asepsis protects key parts and key sites from contamination; sterile gloves do not rescue a contaminated connector or cannula.
  • Plan the field, hand hygiene, PPE, antiseptic, compatible cannula, extension, flush, dressing and sharps disposal before skin preparation.
  • Choose the smallest gauge and shortest appropriate cannula in a suitable distal upper-limb vein for the prescribed therapy, escalating difficult or specialist access.

Key red flags

Infiltration or extravasation

Pain, swelling, blanching, coolness, leakage or resistance during infusion requires immediate stop and drug-specific action.

Local or bloodstream infection

Purulence, spreading erythema, fever or rigors linked to access needs urgent assessment and culture planning.

Missing catheter segment

An incomplete cannula on removal requires immobilisation and urgent senior or vascular management.

Reasoning priorities

01
Therapy and access assessment

Select peripheral versus specialist access and appropriate gauge.

Duration, flow, pH, osmolarity and vesicant risk may make routine peripheral access unsuitable.

Worked reasoning

Worked case: burning during vesicant infusionStop before identifying the rescue

A patient reports burning and swelling around a peripheral cannula during a vesicant infusion.

  1. Stop the infusion immediately, call for experienced help, assess the patient and limb and identify drug, concentration, volume and time.
  2. Reason that extravasation is possible; do not flush and do not automatically remove the cannula because aspiration or a drug-specific antidote may require access.
  3. Disconnect tubing and follow the current medicine-specific local extravasation protocol, including aspiration, elevation, compress and antidote only where specified.
  4. Verify neurovascular status, mark and photograph per consent/policy, arrange serial review and document incident, advice and handover.
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Sources and review status5 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom