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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
RapidPSA

Writing complete and safe prescriptions

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Synopsis

Turn an agreed treatment decision into a complete, unambiguous prescription that another professional can dispense and administer, and that the patient can follow.

  • Check the patient, indication, allergy history and relevant organ function before writing the medicine order; a perfectly formatted prescription can still be clinically wrong.
  • Specify medicine, formulation, strength when needed, dose, route, frequency and duration or review date. Add a maximum dose and indication to an as-needed instruction.
  • Use a leading zero for a dose below one, avoid unnecessary trailing zeros, and write micrograms and units in full where abbreviation could create a dangerous misreading.

Reasoning priorities

01
Current medicine and administration history

Identify duplicate treatment, recent doses and relevant interactions.

Review actual administrations as well as active orders, especially after ambulance or emergency treatment. A new inpatient chart can omit a dose already given elsewhere. Include non-prescription medicines when they share an active ingredient or change the safety of the proposed regimen.

Worked reasoning

Worked exampleWrite an oral antibiotic course completely

Alex Morgan, date of birth 12 May 1962, training identifier LAB001, has a COPD exacerbation for which amoxicillin has been selected. No known drug allergy is confirmed; renal function is stable and normal, swallowing is safe, and no antibiotic doses have yet been given. Available capsules contain 500 mg.

  1. Confirm the selection against the supplied diagnosis and safety information, then use the NICE NG114 adult regimen of amoxicillin 500 mg orally three times daily for 5 days. The clinical decision is a finite course, so an indefinite repeat order would not describe it.
  2. Convert dose to formulation units: 500 mg required divided by 500 mg per capsule equals 1 capsule each dose. Calculate supply as 1 capsule × 3 doses per day × 5 days = 15 capsules; no previous administrations need to be subtracted.
  3. Write the final order with the supplied patient identifiers, prescribing date 7 September 2026, amoxicillin 500 mg capsules, dose 500 mg, oral route, three times daily for 5 days, quantity 15 and the COPD-exacerbation indication. Add the prescriber authentication required by the prescribing system.
  4. Independently verify that 15 capsules divided by 3 daily doses supplies 5 days, that the route is oral and the product is a capsule, and that no allergy or duplicate course is present. Give practical dose-spacing advice and a review plan if symptoms worsen or fail to improve.

Key medicines

Amoxicillin: selected COPD-exacerbation courseFor the suitable adult in the worked case, 500 mg by mouth three times per day over 5 days; one 500 mg capsule per dose gives a total supply of 15 capsules.Antibiotics are selected after clinical assessment, not for every exacerbation. Check penicillin allergy, recent treatment, interactions and renal impairment; severe infection or organ impairment may require a different regimen and assessment.
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Sources and review status5 sources · checked 7 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom