Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
2 min synopsisUK scopeSources checked 27 Aug 2026Clinical review pending
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Escalate
Shock, severe hypoxaemia, respiratory exhaustion, rapidly progressive infiltrates, altered consciousness, inability to protect the airway or need for ventilatory support requires immediate sepsis/critical-care escalation. Do not wait for a CURB65 total or chest radiograph before stabilising ABCDE and giving timely antibiotics.
Synopsis
Diagnose pneumonia clinically and radiographically where appropriate, use CRB65/CURB65 plus judgement to select care, and give severity-matched antibiotics, oxygen and adjunctive treatment with explicit review points.
CAP is an acute lower respiratory infection acquired outside hospital with compatible clinical features and, in hospital, usually new radiographic shadowing not explained by another cause.
Assess ABCDE, SpO2, sepsis physiology, ability to take oral medicines, frailty/comorbidity and social support before scoring severity.
CRB65 in the community and CURB65 in hospital support risk assessment: Confusion, urea above 7 mmol/L, respiratory rate at least 30/min, low BP, age 65 or over; each scores 1.
Key red flags
High-severity CAP
CURB65 3-5 and/or clinical shock, profound hypoxaemia, rapid progression or need for ventilatory/vasopressor support. Seek critical-care input early and treat promptly.
Investigation priorities
01
CRB65/CURB65 plus clinical judgementFirst step
Estimate mortality risk and guide place/intensity of care.
Management branches
First hourAssess severity and treat
Suspected CAP with systemic illness or hospital presentation.
ABCDE, SpO2, sepsis assessment and CRB65/CURB65; obtain CXR and relevant cultures promptly without delaying antibiotics in unstable disease.
Give oxygen to 94-98%, or 88-92% if hypercapnic risk. Give oral antibiotic first if feasible; use IV when high severity, vomiting, absorption concern or critical illness requires it.
Key medicines
Amoxicillin500 mg orally three times daily for 5 days; higher doses may be used for severe infection according to BNF/renal function.
Doxycycline200 mg orally on day 1, then 100 mg once daily on days 2-5.
National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.