Synopsis
Confirm true lower-respiratory bleeding, protect the airway in life-threatening haemoptysis, and identify malignancy, infection, bronchiectasis, vascular disease and treatment-related bleeding through a severity-led investigation pathway.
- First confirm the source: haemoptysis is coughed from below the larynx, while epistaxis, oral bleeding and haematemesis require different pathways.
- Severity is physiological, not purely volumetric. Airway flooding, impaired gas exchange, haemodynamic instability or continuing brisk bleeding defines an emergency even when volume is uncertain.
- Ask about lung-cancer risk, bronchiectasis, tuberculosis exposure, infection, pulmonary embolism, autoimmune disease, recent procedures and anticoagulant or antiplatelet treatment.
- Unexplained haemoptysis in a person aged forty or over meets NICE criteria for a suspected lung-cancer pathway referral; an abnormal radiograph can trigger referral at any relevant age.
- Chest radiography is a useful start in stable bleeding, but contrast-enhanced CT or CT angiography usually provides better localisation and cause assessment; CTPA is selected when embolism is the question.
- Bronchoscopy is important for airway control, clot extraction, central lesions and persistent bleeding; it complements rather than automatically replaces CT.
- Review anticoagulants, platelet inhibitors and coagulation abnormalities immediately, but do not assume treatment is the underlying cause until structural disease has been considered.
- Bronchial arteries cause most severe haemoptysis; bronchial-artery embolisation is a key definitive treatment for ongoing or recurrent significant bleeding.
Key red flags
Active bleeding with inability to clear blood, falling saturation, respiratory distress, reduced consciousness, hypotension or a rapidly filling airway requires simultaneous resuscitation and haemorrhage control. Reported millilitres should not delay escalation.
Unexplained recurrent bleeding, weight loss, persistent cough, hoarseness, clubbing, lymphadenopathy or focal/recurrent radiographic change is concerning, especially with age over forty, smoking or asbestos exposure. Minor streaking can still be the presenting feature.
Pleuritic pain, sudden breathlessness, syncope, hypoxaemia or thrombosis risk raises pulmonary embolism. Recurrent unexplained hypoxaemia, telangiectasia or family history may suggest pulmonary arteriovenous malformation.
Haemoptysis with diffuse infiltrates, falling haemoglobin, hypoxaemia and renal, skin or systemic inflammatory features raises pulmonary capillaritis or another alveolar-haemorrhage syndrome. Haemoptysis may be absent despite substantial alveolar bleeding.
Investigation priorities
Determine whether haemoptysis is immediately threatening airway, ventilation or circulation.
Management branches
Airway contamination, gas-exchange failure, haemodynamic compromise or continuing brisk haemoptysis.
- Activate major clinical support including anaesthesia, respiratory, interventional radiology and thoracic surgery; use high-flow suction, monitoring, large-bore access and blood preparation while protecting staff and patient.
- If the bleeding side is known, position that lung dependent where feasible to protect the other lung; provide oxygen and ventilation support, recognising that a large single-lumen airway may be required for suction and bronchoscopy.
- Withhold and reverse clinically significant anticoagulation according to the specific agent, timing, renal function and local major-bleeding protocol; correct major thrombocytopenia or coagulopathy with haematology input.
- Use urgent contrast CT/angiography if the patient can be transferred safely, or bronchoscopy when airway control cannot wait; proceed to bronchial-artery embolisation for a suitable ongoing systemic arterial source.
- Plan surgery only for selected uncontrolled bleeding or a surgically correctable lesion because emergency resection carries substantial risk.
Blood-streaking or small-volume haemoptysis with stable airway, oxygenation and haemodynamics.