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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Occupational asthma

Respiratory · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
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Escalate

Treat an acute asthma attack according to the current local emergency pathway, remove the person from the immediate exposure and escalate for severe or life-threatening features. A major irritant release can affect several workers and requires workplace emergency procedures, decontamination advice where relevant and early occupational, respiratory and emergency-service coordination.

Synopsis

Recognise asthma caused or worsened by work, preserve the opportunity for objective diagnosis, and coordinate exposure control, clinical treatment and confidential employment advice.

  • Ask every working-age adult with new or deteriorating asthma what they do, which agents they handle, whether symptoms change across shifts and whether colleagues are affected.
  • Occupational asthma means new asthma caused by work; work-exacerbated asthma is pre-existing or coincidental asthma made worse by workplace conditions, and the distinction affects prevention and prognosis.
  • Sensitiser-induced disease often follows a symptom-free latency period, whereas irritant-induced asthma may follow a substantial exposure without allergic sensitisation.
  • Improvement on rest days or holidays supports a work relationship but is not diagnostic because treatment, infections and exposure patterns also change.
  • Arrange early specialist occupational-respiratory assessment; delay can allow continued injury and may erase the chance to demonstrate an exposure-response pattern.
  • Serial peak expiratory flow is most informative while the person is still in the relevant work, provided continued exposure is clinically safe.
  • Do not advise abrupt resignation as a diagnostic strategy; health, income, legal rights and safer redeployment must be considered with informed specialist support.
  • Exposure control is disease-modifying. Inhalers reduce inflammation and symptoms but do not make continued uncontrolled exposure safe.
  • Communicate with an employer or occupational-health service only with the person's informed consent, except where a separate overriding legal duty has been established and explained.
  • Local reporting, occupational-disease and workplace safety duties vary across UK jurisdictions and roles; use current HSE or devolved guidance and specialist advice.

Key red flags

Irritant-induced asthma

Asthma begins after a clearly described high-level irritant event or repeated substantial irritant exposures, without a sensitisation latency pattern. Document the event, co-workers, emergency attendance and exposure controls precisely.

Alternative occupational lung disease

Fever, systemic upset, inspiratory crackles, reduced gas transfer, focal imaging, fixed obstruction or progressive breathlessness should prompt consideration of hypersensitivity pneumonitis, silicosis, COPD, infection, bronchiolitis or another occupational disorder.

High-risk ongoing exposure

Rapid worsening, attacks requiring urgent care, a major spill, inadequate respiratory protection or several affected workers makes continued workplace challenge unsafe and requires immediate exposure removal and specialist coordination.

Investigation priorities

01
Detailed job, task and exposure chronologyFirst step

Identify plausible agents and the temporal disease pattern.

Management branches

First reviewAsk beyond the job title

Adult-onset asthma, unexplained deterioration or symptoms linked to work.

  1. List current and past jobs, then break each job into tasks, products, airborne agents, spills, ventilation, respiratory protection and affected colleagues.
  2. Build a calendar of symptom onset, latency, shift timing, weekends, holidays, sick leave, treatment changes and major exposure events.
  3. Assess current asthma severity and immediate exposure safety, provide an action plan, and arrange objective asthma testing without delaying urgent treatment.
  4. Refer early to a clinician experienced in occupational asthma while exposure-response measurements remain feasible and employment advice can be coordinated.

Key medicines

Low-dose inhaled corticosteroid-formoterol anti-inflammatory relieverFor eligible people aged twelve and over, use the exact inhaler and as-needed regimen specified by NICE and the local formulary after technique training.Confirm the device is licensed for the intended AIR or MART regimen and provide a personalised action plan. Increasing use signals poor control or ongoing exposure; inhaled treatment does not neutralise a causal workplace sensitiser.
Maintenance inhaled corticosteroid-formoterol MART regimenUse the locally selected low- or moderate-dose maintenance schedule with the same inhaler as reliever, following NICE steps and product limits.Check adherence, technique, triggers and diagnosis before escalation. Device strengths and maximum inhalations differ; repeated oral corticosteroid need or continuing work-related attacks requires specialist review and exposure intervention, not automatic dose escalation alone.
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Sources and review status5 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • BTS Clinical Statement on occupational asthmaUK specialist statement covering diagnosis, causation, prevention and management.
  • NICE NG244 Occupational asthma pathwayNational referral and assessment pathway linked from current asthma guidance.
  • NICE NG245 Asthma recommendationsCurrent objective diagnosis and chronic treatment recommendations.
  • HSE Work-related asthma overviewWorkplace sensitisers, irritants and prevention responsibilities.
  • Royal College of Physicians occupational asthma guidanceSerial PEF and specialist diagnostic principles.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom