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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
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Fistula thrombosis and stenosis

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Acute access occlusion

Abrupt loss of thrill or bruit, inability to obtain dialysis flow, or a newly hard painful access suggests thrombosis and threatens both dialysis delivery and future access.

Action: Do not repeatedly needle the silent access; contact the dialysis and vascular-access team immediately for same-day assessment, check dialysis urgency and potassium, and arrange prompt endovascular or surgical salvage.

Synopsis

Recognise clinical fistula dysfunction before occlusion, confirm the lesion through timely circuit imaging, and salvage acute thrombosis by removing thrombus and correcting the culprit stenosis.

  • An abruptly absent thrill or bruit is a time-sensitive thrombosed access: stop repeated cannulation and obtain same-day dialysis and access-team review for salvage.
  • Salvage must address both thrombus and the underlying culprit stenosis; thrombectomy without lesion treatment invites early re-occlusion.
  • Treat stenosis when clinical dysfunction and a radiologically significant lesion agree; do not perform pre-emptive angioplasty for an incidental narrowing without clinical indicators.

Key red flags

Absent thrill or bruit is acute thrombosis until proved otherwise and should trigger same-day access assessment rather than routine outpatient imaging.

Severe hyperkalaemia, pulmonary oedema, uraemic complication or missed essential dialysis requires parallel emergency dialysis planning through safe alternative access.

A painful erythematous thrombosed access with fever or purulence may be infected; obtain blood cultures and avoid blind declotting through an infected field.

Rapid swelling, neurological deficit or hand ischaemia after intervention suggests bleeding, compartment pressure, embolisation or arterial injury and needs urgent vascular review.

Acute thrombosis

Sudden loss of the continuous thrill and bruit, a firm non-compressible segment and inability to aspirate blood are typical; pain may be modest, so absence of pain is not reassuring.

Infected thrombosis

Fever, rigors, purulent drainage, erythema, fluctuance or exposed material accompanying thrombosis raises a different emergency because declotting may disseminate infection.

Investigation priorities

01
Immediate access and dialysis assessmentFirst step

Confirm thrill or bruit loss, examine the whole circuit and limb, check last successful dialysis, volume state and urgent biochemical need.

02
Duplex ultrasound — preferred initial circuit imagingPreferred

Locate thrombus, quantify inflow and outflow, identify stenosis, aneurysm or collection, and assess adjacent arteries and veins without iodinated contrast.

Management branches

Emergency pathwayAbruptly thrombosed fistula

Use for a previously functioning fistula with absent thrill or bruit, failed cannulation or confirmed acute thrombotic occlusion.

  1. Stop repeated needling, establish last dialysis and biochemical urgency, examine for infection, limb ischaemia, swelling and bleeding, and alert the access team the same day.
  2. Arrange urgent duplex or direct procedural imaging and choose endovascular or surgical salvage according to anatomy, expertise, infection, prior treatment and the person's access plan.
Routine dysfunction pathwayClinical indicators without occlusion

Use for new cannulation difficulty, abnormal examination, prolonged bleeding, falling adequacy, pressure alarms or arm swelling while flow persists.

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Sources and review status3 sources · checked 13 Sept 2026 · clinical review pending
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Apply principles in context and verify current guidance when a decision affects care. Source check completed 13 Sept 2026; clinical approval remains outstanding.

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom