Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.
2 min synopsisUK scopeSources checked 27 Aug 2026Clinical review pending
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Life-threatening bleeding precedes part salvage
Complete or near-complete amputation can exsanguinate rapidly, while crush, contamination, hypothermia and multisystem trauma determine survival and whether replantation can produce a useful limb.
Action: Use catastrophic-haemorrhage control and ABCDE, apply direct pressure, packing or the most distal effective tourniquet without blind clamping, activate major haemorrhage and trauma transfer, cover the stump and give open-injury antibiotics, wrap the part in saline-moistened gauze inside a sealed bag placed in iced water without direct ice contact, and contact the replantation centre immediately.
Synopsis
Prioritise survival and haemorrhage control, protect the residual limb without blind clamping, package an amputated part correctly, minimise warm ischaemia through direct specialist transfer, and integrate replantation, revision amputation and lifelong rehabilitation decisions.
Control catastrophic haemorrhage first with direct pressure, packing or a commercial tourniquet placed as distally as effectively possible; record the exact application time and never use blind vascular clamps.
Do not shorten, complete or repeatedly debride the stump in the emergency department. Cover with a sterile saline-moistened dressing and protect bone, nerves and vessels for specialist revision or replantation.
Handle the part gently, remove only gross loose contamination, wrap it in sterile gauze moistened with saline and place it inside a sealed, labelled plastic bag.
Key red flags
Uncontrolled stump bleeding, shock, coagulopathy, hypothermia or associated torso and pelvic injury requires simultaneous resuscitation and operative haemorrhage control; replantation discussion must not delay survival care.
Investigation priorities
01
First-line trauma physiologyFirst stepFirst line
Identify haemorrhage, hypothermia, coagulopathy and associated life threat.
Management branches
ResuscitationControl bleeding and preserve options
A complete or near-complete traumatic amputation arrives with potential major haemorrhage.
Run catastrophic haemorrhage and ABCDE care, using pressure, packing or the most distal effective tourniquet and recording its time.
Activate blood-component resuscitation, TXA when indicated, warming and immediate trauma, orthopaedic and plastic or vascular support.
Key medicines
Tranexamic acid for significant traumatic bleedingFor an adult within 3 hours of injury, give 1 g intravenously over 10 minutes followed by 1 g intravenously over 8 hours when active or suspected major bleeding meets the trauma protocol.
Immediate intravenous open-injury prophylaxisGive the trauma network's specified intravenous agent at the current adult weight-based dose as soon as possible and ideally within 1 hour; record allergy, agent, dose and time and apply exposure-specific additions through microbiology.
National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.