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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Traumatic amputation and part preservation

Musculoskeletal medicine and orthopaedics · UK scope · Sources checked 27 Aug 2026 · Clinical review pending

RapidFull
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Life-threatening bleeding precedes part salvage

Complete or near-complete amputation can exsanguinate rapidly, while crush, contamination, hypothermia and multisystem trauma determine survival and whether replantation can produce a useful limb.

Action: Use catastrophic-haemorrhage control and ABCDE, apply direct pressure, packing or the most distal effective tourniquet without blind clamping, activate major haemorrhage and trauma transfer, cover the stump and give open-injury antibiotics, wrap the part in saline-moistened gauze inside a sealed bag placed in iced water without direct ice contact, and contact the replantation centre immediately.

Synopsis

Prioritise survival and haemorrhage control, protect the residual limb without blind clamping, package an amputated part correctly, minimise warm ischaemia through direct specialist transfer, and integrate replantation, revision amputation and lifelong rehabilitation decisions.

  • Control catastrophic haemorrhage first with direct pressure, packing or a commercial tourniquet placed as distally as effectively possible; record the exact application time and never use blind vascular clamps.
  • Do not shorten, complete or repeatedly debride the stump in the emergency department. Cover with a sterile saline-moistened dressing and protect bone, nerves and vessels for specialist revision or replantation.
  • Handle the part gently, remove only gross loose contamination, wrap it in sterile gauze moistened with saline and place it inside a sealed, labelled plastic bag.
  • Place the sealed bag in a second container containing iced water. Do not let tissue touch ice, freeze it, immerse it directly or place it loose in a refrigerator.
  • Label identity, side, anatomical level, injury time, cooling time and contamination and keep the part with the patient during direct trauma or replantation-centre transfer.
  • Contact the receiving specialist immediately with age, hand dominance, occupation, level, mechanism, contamination, warm and cold times, associated injuries and physiological status; do not await all imaging.
  • Replantation decisions consider life threat, level, muscle mass, ischaemia, crush or avulsion zone, contamination, comorbidity and likely useful function; a severity score cannot make the decision alone.
  • Begin antibiotics, tetanus care, pain and psychological support, then plan stump or replanted-limb monitoring, rehabilitation, prosthetics and return-to-life goals from admission.

Key red flags

Uncontrolled stump bleeding, shock, coagulopathy, hypothermia or associated torso and pelvic injury requires simultaneous resuscitation and operative haemorrhage control; replantation discussion must not delay survival care.

A partial amputation with a narrow tissue bridge, absent distal perfusion, venous congestion or progressive neurological loss is a dysvascular limb and must not be completed in the emergency department.

Direct ice or freezer contact, immersion in water, dry storage or failure to cool the sealed part accelerates tissue injury and can destroy otherwise viable replantation options.

Crush, avulsion, farm or water contamination and prolonged ischaemia reduce replantation feasibility and increase compartment, infection and systemic rhabdomyolysis risk, but specialist teams rather than a bedside score make the final decision.

Investigation priorities

01
First-line trauma physiologyFirst stepFirst line

Identify haemorrhage, hypothermia, coagulopathy and associated life threat.

Management branches

ResuscitationControl bleeding and preserve options

A complete or near-complete traumatic amputation arrives with potential major haemorrhage.

  1. Run catastrophic haemorrhage and ABCDE care, using pressure, packing or the most distal effective tourniquet and recording its time.
  2. Activate blood-component resuscitation, TXA when indicated, warming and immediate trauma, orthopaedic and plastic or vascular support.
  3. Cover the stump without blind clamps or bedside shortening, give network open-injury prophylaxis and assess tetanus risk.
  4. Splint a near-amputation in alignment, repeat its perfusion and nerve examination and do not divide the remaining bridge.

Key medicines

Tranexamic acid for significant traumatic bleedingFor an adult within 3 hours of injury, give 1 g intravenously over 10 minutes followed by 1 g intravenously over 8 hours when active or suspected major bleeding meets the trauma protocol.Do not delay surgical haemorrhage control, and do not initiate after 3 hours unless evidence of hyperfibrinolysis supports it; adjust maintenance exposure in significant renal impairment and review thrombosis risk.
Immediate intravenous open-injury prophylaxisGive the trauma network's specified intravenous agent at the current adult weight-based dose as soon as possible and ideally within 1 hour; record allergy, agent, dose and time and apply exposure-specific additions through microbiology.Farm, aquatic, sewage, bite and resistant-organism exposure changes coverage; renal function, pregnancy and immediate allergy alter dose or agent, and antibiotics never replace tissue excision and timely cover.
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Sources and review status6 sources · checked 27 Aug 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 27 Aug 2026; clinical approval remains outstanding.

  • NICE NG37 Fractures complex: assessment and management
  • NICE NG39 Major trauma: assessment and initial management
  • BOASt - Diagnosis and management of arterial injuries associated with musculoskeletal trauma
  • BOASt - Open Fractures
  • Cyklokapron 100 mg per mL solution for injection or infusion SmPC
  • UK Health Security Agency Green Book chapter 30: tetanus

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom