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Educational draft · awaiting clinical reviewUse Rapid for revision, not patient-care decisions. Check current national and local guidance and the BNF or BNFC before acting.

Psychiatric assessment after overdose

Psychiatry · UK scope · Sources checked 7 Sept 2026 · Clinical review pending

RapidFull
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Poisoning and suicidal crisis can coexist

A patient may look well despite a potentially serious ingestion, and apparent regret does not establish that further self-harm risk has resolved.

Action: Assess ABCDE, glucose, ingestion details and immediate safety, obtain poison-specific advice and treatment, and request mental-health assessment while medical care proceeds.

Synopsis

Combine toxicological care with an early psychosocial assessment, formulate ongoing safety needs and arrange a specific shared plan after intentional self-poisoning.

  • Self-harm includes intentional self-poisoning irrespective of the stated purpose or apparent lethality.
  • Begin psychosocial assessment at the earliest opportunity alongside physical treatment, rather than waiting for every medical investigation to finish.
  • Intoxication is not an automatic exclusion; assess the person's ability to engage and review repeatedly if they cannot yet participate.
  • Explore the circumstances, meaning and function of the overdose, current thoughts, previous episodes, strengths and practical support.
  • Do not use numerical risk scales or low, medium and high categories to predict suicide or determine discharge.
  • Create a collaborative safety plan with warning signs, coping actions, supportive contacts, emergency access and safer access to medicines.
  • With ongoing safety concerns, NICE recommends initial aftercare within forty-eight hours of the psychosocial assessment.

Key red flags

An uncertain ingestion time, sustained-release preparation, mixed overdose, impaired consciousness, seizure or ECG abnormality requires a toxicological plan before discharge is considered.

Persistent intent, preparations for another attempt, access to lethal means, severe agitation, psychosis or an unsafe home environment needs prompt senior mental-health review and protection.

Investigation priorities

01
Poison-specific medical assessmentFirst step

Determine the exposure's likely effects and the required treatment or observation timeline.

Management branches

Arrival and stabilisationProvide physical and emotional care together

The patient presents following deliberate ingestion or a concerning overdose of uncertain intent.

  1. Treat physiological compromise, establish the exposure timeline and institute the specific toxicology monitoring and treatment plan.
  2. Offer a private supportive space and early liaison assessment, explaining the process and reducing unnecessary barriers caused by stigma or distress.
  3. Review observation needs, access to further medicines and safeguarding while preserving dignity and involving a chosen supporter appropriately.

Key medicines

Antidotes and acute poisoning treatmentSelect the antidote, loading dose, route, infusion schedule, repeat investigations and stopping criteria from the identified poison's TOXBASE pathway, using NPIS advice for mixed, delayed, staggered or uncertain exposure. Do not apply one antidote schedule to all overdoses.Dose and timing depend on substance, formulation, body weight, ingestion pattern and organ function; the relevant entry must be available at prescribing. No generic antidote reverses intentional self-poisoning as a category.
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Sources and review status4 sources · checked 7 Sept 2026 · clinical review pending+
Sources

Sources and review status

National guidance is shown before implementation-dependent detail. Typical adult dose examples remain subject to patient factors, contraindications and the live BNF or specialist protocol. Source check completed 7 Sept 2026; clinical approval remains outstanding.

  • NICE NG225 self-harm recommendationsEarly psychosocial assessment, risk formulation, discharge and initial aftercare.
  • NPIS TOXBASE clinical toxicology informationUK poison-specific decision support; individual clinical entries require registered access.
  • NHS SPS poisoning and toxicity resourcesCurrent NHS guidance on selecting TOXBASE and NPIS advice.
  • Mental Capacity Act Code of PracticeEngland and Wales decision-specific capacity and emergency care principles.

Editorial contact: Doctor’s Passport editorial team. Source-check date is separate from clinical approval. Report a content problem · Content changes

Authoring stateRapid draftClinical stateAwaiting reviewJurisdictionUnited Kingdom